Вид документа : Статья из журнала Шифр издания : 57/E 97 Автор(ы) : Chereshnev V. A., Gankovskaya L. V., Koval'chuk L. V., Chereshneva M. V., Gankovskaya O. A. Заглавие : Expression of TLR9 and BD-2 protein genes in corneal cells of mice of different strains with herpetic keratitis Место публикации : Bulletin of experimental biology and medicine. - 2012. - Vol. 153, № 2. - С. 236-239 Примечания : Bibliogr. : p. 239 (11 ref.) ББК : 57 Предметные рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): innate immunity--herpetic infection--keratitis Аннотация: The dynamics of gene expression of two proteins, TLR9 (one of the key receptors recognizing CpG repeats of herpes virus DNA) and beta-defensin 2 (antibacterial peptide), was studied on the model of herpetic keratitis in C57Bl/6 and BALB/c mice. New data on differences in TLR9 gene expression in mice of the two strains infected with the virus were obtained. Reduced TLR9 gene expression in the cornea of C57Bl/6 mice was associated with their high sensitivity to infection caused by herpes simplex 1 virus Доп.точки доступа: Chereshnev, V. A.; Gankovskaya, L. V.; Koval'chuk, L. V.; Chereshneva, M. V.; Gankovskaya, O. A. |