Вид документа : Статья из журнала Шифр издания : 57/I-57 Автор(ы) : Kuyukina M. S., Ivshina I. B., Gein S. V., Chereshnev V. A. Заглавие : In vitro immunomodulating activity of biosurfactant glycolipid complex from Rhodococcus ruber Место публикации : Herald of the Russian Academy of Sciences. - 2007. - Vol. 77, № 5. - С. 326-330 ББК : 57 Предметные рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): actinobacteria--rhodococcus ruber--biosurfactant Аннотация: The biosurfactant glycolipid complex synthesized by Rhodococcus ruber actinobacteria is not toxic and exhibits no appreciable effect on proliferative activity of peripheral blood leukocytes. In the monocyte fraction, the biosurfactant activates the production of IL-1 beta and TNF-alpha cytokines without modifying the production of IL-6. In the mononuclear fraction, the glycolipid biosurfactant exhibited no effects on the production of IL-1 beta, TNF-alpha, and IL-6. These results indicate good prospects for further studies of immunomodulating and antitumor activities of biosurfactant drug Доп.точки доступа: Kuyukina, M. S.; Ivshina, I. B.; Gein, S. V.; Chereshnev, V. A.