S 98 Synthesis of Aminomethyl Derivatives of 3-Methyl-4,7-dihydro-3H-imidazo[4,5-d][1,2,3]triazin-4-one [Text] / G. L. Rusinov, R. I. Ishmetova, I. S. Selezneva, T. A. Kalugina // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2000. - Vol. 36, № 6. - P873-876 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: New aminomethyl derivatives of 3-methyl-4,7-dihydro-3H-imidazo[4,5-d][1,2,3]triazin-4-one??were synthesized by Mannich reaction. These Mannich bases is also possible to prepare by reaction of??7(5)-hydroxymethyl-3-methyl-4,7(5)dihydro-3H-imidazo[4,5-d][1,2,3]triazin-4-one with amines.The??compounds obtained exist in solutions as mixtures of N5??and N7 isomers,and the fraction of the latter grows??with the polarity of the solvent. |