S 98 Synthesis of hydrogels based on silicon polyolates [Electronic resource] / T. G. Khonina, E. V. Shadrina, A. A. Boyko, O. N. Chupakhin, L. P. Larionov, A. A. Volkov, V. D. Burda // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P75-80 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ORGANOSILICON COMPOUNDS -- DIOLS -- GLYCEROL Аннотация: Biologically active hydrogels based on silicon polyolates, which are the products of reactions of tetraethoxy- and methyltriethoxysilanes with polyols (1,2-propanediol, glycerol, polyethylene glycol), were synthesized. The optimal conditions for hydrogel formation and hydrogel composition were determined. The acute toxicity and transcutaneous and wound-healing activities of the synthesized compounds were studied. The experimental results show that hydrogels based on silicon polyolates can be recommended for further preclinical and clinical tests with the purpose of their use in medical practice both as self-sufficient agents and ointment bases of pharmaceutical compositions with wound-healing, regenerative, and transcutaneous action \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2010, 59 (1), 75-80.pdf |