T 44 The antiaggregant action of 2-morpholino-5-(thienyl-2)-6-H-1,3,4-thiadiazine in in vitro and ex vivo experiments [Electronic resource] / I. S. Loginova, V. A. Makarov, O. N. Chupakhin, L. P. Sidorova, N. M. Perova, V. L. Rusinov // Eksperimental'naia i klinicheskaia farmakologiia . - 2013. - Vol.76, №2. - С. 13-16. - Библиогр.: с. Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ANIMAL -- BLOOD CLOTTING -- CYTOLOGY Аннотация: The influence of 2-morpholino-5-(thienyl-2)-6-H-1,3,4-thiadiazine (H-29) on the platelet aggregation has been studied in experiments on donor plasma in vitro. It is established that H-29 causes a decrease in the platelet interaction induced by ADP and arachidonic acid. The influence of H-29 on platelet aggregation was also studied in ex vivo experiments with intravenous and oral administration, and some parameters of plasmatic hemostasis were evaluated |