Вид документа : Статья из журнала Шифр издания : 54/S 98 Автор(ы) : Sevenard D. V., Khomutov O. G., Koryakova O. V., Sattarova V.V., Kodess M. I., Stelten J., Loop I., Lork E., Pashkevich K. I., Roeschenthaler G.-V. Заглавие : Syntheses of novel 4-polyfluoroalkyl-substituted 5,6-oligomethylene pyrimidines Место публикации : Synthesis. - 2000. - № 12. - С. 1738-1748 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 2-Acylcycloalkanones having polyfluoroalkyl groups react with guanidine, urea, thiourea, methylisothiourea, benzamidine, guanylthiourea, dicyanodiamide, and trifluoroacetylurea by Lewis-acid catalysis to form the corresponding 5,6-oligomethylene pyrimidines. A decrease in the yields along with increase of polyflyoroalkyl substituent length in the molecule of the starting 1,3-diketone was observed in the case of reagents with lower nucleophilicity (urea, thiourea, dicyanodiamide). The pyrimidines obtained from aromatic aldehydes showed E-configuration with respect to the arylidene double bond. Tautomeric structures as a function of the substituent in 2 position in the pyrimidine ring both in liquid and solid state were investigated by X-ray diffraction, IR and NMR spectroscopy. Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Sevenard, D. V.; Севенард Дмитрий Викторович; Khomutov, O. G.; Хомутов Олег Геннадьевич; Koryakova, O. V.; Корякова Ольга Васильевна; Sattarova, V.V.; Kodess, M. I.; Кодесс Михаил Исаакович; Stelten, J.; Loop, I.; Lork, E.; Pashkevich, K. I.; Пашкевич Казимир Иосифович; Roeschenthaler, G.-V.