Вид документа : Статья из журнала Шифр издания : 54/B 57 Автор(ы) : Saloutin V. I., Burgart Ya. V., Kuzueva O. G., Kappe C.O., Chupakhin O. N. Заглавие : Biginelli condensations of fluorinated 3-oxo esters and 1,3-diketones Место публикации : Journal of Fluorine Chemistry. - 2000. - Vol. 103, № 3. - С. 17-23 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Condensation of fluorinated 3-oxo esters or 1,3-diketones with benzaldehyde and (thio)urea results in the diastereoselective formation of 4-fluoroalkyl-4-hydroxy-2-oxo(thioxo)-6-phenyl-hexahydropyrimidine-5-carboxylates from which by dehydration under acidic conditions the corresponding 6-fluoroalkyl-2-oxo(thioxo)-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylates were obtained. Under the same conditions, hexafluoroacetylacetone furnishes 4,6-dihydroxy-4,6-di(trifluoromethyl)-hexahydropyrimidin-2-one. Some further reactions of these pyrimidine derivatives leading to fused heterocycles are described.???? Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Saloutin, V. I.; Burgart, Ya. V.; Бургарт Янина Валерьевна; Kuzueva, O. G.; Кузуева Ольга Георгиевна; Kappe, C.O.; Chupakhin, O. N.