Вид документа : Статья из журнала Шифр издания : 54/N 52 Автор(ы) : Tretyakov E. V., Utepova I. A., Varaksin M. V., Tolstikov S. E., Romanenko G. V., Bogomyakov A. S., Stass D. V., Ovcharenko V., Chupakhin O. N. Заглавие : New approach to synthesis of nitronyl and imino nitroxides based on S(N)(H) methodology Место публикации : ARKIVOC. - 2011. - Part 8. - С. 76-98: ил. Примечания : Bibliogr. : p. 98 (36 ref.) ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: It is shown that S(N)(H) approach opens new possibilities in the synthesis of polyfunctional nitronyl and imino nitroxides. It is found that the interaction of 4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-3-oxide-1-oxyl lithium salt Li1 with 3,6-diaryl-1,2,4-triazines leads to formation of the corresponding triazines bearing nitronyl nitroxide or imino nitroxide substituent at position 5 of the heterocycle. The reaction of Li1 with pyridazine-N-oxide gives rise to nitroxide with buten-3-ynyl substituent 5. Spin-labeled 5 could be readily transformed by the use of 1,3-dipolar and nucleophilic addition reactions, as well as oxidative coupling, that gives a large group of new paramagnets: 2-(1H-pyrazol-5-yl)vinyl-, 2-ethynylcyclopropyl-, 2-(3-(ethoxycarbonyl) isoxazol-5-yl)vinyl-, 1-(pyrrolidin-1-yl)but-3-ynyl-substituted nitronyl nitroxide and a diradical -2,2'-((1E,7E)-octa-1,7-dien-3,5-diyne-1,8-diyl)bis(4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazol-3-oxide-1-oxyl). The new nitroxides were characterized by X-ray single crystal data, ESR and static magnetic susceptibility measurements Держатели документа: Центральная научная библиотека УрО РАН Доп.точки доступа: Tretyakov, E. V.; Utepova, I. A.; Varaksin, M. V.; Tolstikov, S. E.; Romanenko, G. V.; Bogomyakov, A. S.; Stass, D. V.; Ovcharenko, V.; Chupakhin, O. N.