Вид документа : Статья из журнала Шифр издания : 54/S 98 Автор(ы) : Irgashev R. A., Karmatsky A. A., Rusinov G. L., Charushin V. N. Заглавие : Synthesis of 4-(thien-2-yl)-substituted coumarins through Lewis acid catalyzed Michael addition of thiophenes to 3-benzoylcoumarins followed by oxidation [Электронный ресурс] Место публикации : Tetrahedron Letters. - 2014. - Vol.55, №26. - С. 3603-3606 Систем. требования: http://www.sciencedirect.com/science/article/pii/S0040403914007497 Примечания : 08.08.2014 ББК : 54 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): thiophenes--3-benzoylcoumarins--lewis acid Аннотация: 3-Benzoyl-4-(thien-2-yl)coumarins have been obtained in good yields according to the SNH addition–oxidation protocol, involving the diastereoselective addition of thiophenes at C-4 of 3-benzoylcoumarins under BBr3 catalysis, followed by oxidation of the intermediate 3,4-trans-3-benzoyl-4-(thien-2-yl)-3,4-dihydrocoumarins with DDQ. This two-step procedure can be regarded as nucleophilic substitution of hydrogen (SNH) on the heterocyclic ring of coumarins Доп.точки доступа: Irgashev, R. A.; Karmatsky, A. A.; Rusinov, G. L.; Русинов Геннадий Леонидович; Charushin, V. N.