Вид документа : Статья из журнала Шифр издания : Г/A 10 Автор(ы) : De A., Majee A., Santra S., Khalymbadzha I. A., Zyryanov G. V. Заглавие : A practicable synthesis of 2,3-disubstituted 1,4-dioxanes bearing a carbonyl functionality from α,β-unsaturated ketones using the williamson strategy Место публикации : Organic & biomolecular chemistry. - 2021. - Vol. 19, № 6. - С. 1278-1286 ББК : Г Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: We have observed that a reagent combination of NaIO4 and NH2OH·HCl reacts with α,β-unsaturated ketones followed by the nucleophile ethylene glycol allowing the synthesis of 2,3-disubstituted 1,4-dioxanes using cesium carbonate as a base under Williamson ether synthesis. This reaction is useful for the synthesis of functionalized 1,4-dioxane having a carbonyl functionality. A variety of 2,3-disubstituted 1,4-dioxanes have been synthesized using these reaction conditions. A probable reaction mechanism has also been proposed. Доп.точки доступа: De, A.; Majee, A.; Santra, S.; Khalymbadzha, I. A.; Zyryanov, G. V.