Вид документа : Статья из журнала Шифр издания : Автор(ы) : Demin A. M., Vakhrushev A. V., Valova M. S., Minin A. S., Kuznetsov D. K., Uimin M. A., Shur V. Ya., Krasnov V. P., Charushin V. N. Заглавие : Design of SiO2/aminopropylsilane-modifi ed magnetic Fe3O4 nanoparticles for doxorubicin immobilization Место публикации : Russian chemical bulletin. - 2021. - Vol. 70, № 5. - С. 987-994 Предметные рубрики: ХИМИЧЕСКИЕ НАУКИ Ключевые слова (''Своб.индексиров.''): magnetic nanoparticles --n-phosphonomethyliminodiacetic acid--doxorubicin--sio2 coating--sorption Аннотация: Surface modifi cation of magnetic nanoparticles (MNPs) with tetramethylorthosilicate and 3-aminopropyltrimethoxysilane was studied. The use of N-phosphonomethyliminodiacetic acid for the stabilization of the initial MNPs can signifi cantly increase the coating thickness and specifi c surface area of SiO2/APS-modifi ed (APS is 3-aminopropylsilane) MNPs. The possibility of sorption of antitumor drug doxorubicin (DOX) on the synthesized nanoparticles was studied. The degree of sorption of DOX increases with an increase in the specifi c surface area of the particles. Доп.точки доступа: Demin, A. M.; Vakhrushev, A. V.; Valova, M. S.; Minin, A. S.; Kuznetsov, D. K.; Uimin, M. A.; Shur, V. Ya.; Krasnov, V. P.; Charushin, V. N.