K 75 Korolevskaya, L. V. Alkylhydroxybenzenes modify immune complex size [Electronic resource] / L. V. Korolevskaya, K. V. Shmagel, V. A. Chereshnev // Doklady biochemistry and biophysics. - 2012. - Vol. 446, № 1. - P229-230. - Bibliogr. : p. 230 (9 ref.) Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ALKYLHYDROXYBENZENES -- IMMUNE COMPLEX \\\\expert2\\NBO\\Doklady Biochemistry and Biophysics\\2012, v.446, № 1. p.229-230.pdf |
S 54 Shmagel, K. V. Molecular bases of immune complex pathology [Electronic resource] / K. V. Shmagel, V. A. Chereshnev // Biochemistry. - 2009. - Vol. 74, № 5. - P469-479. - Bibliogr. : p. 477-479 (126 ref.) Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): IMMUNE COMPLEXES -- COMPLEMENT -- CR1 RECEPTORS Аннотация: The binding of antigens with antibodies forms immune complexes in the body. Usually these complexes are eliminated by the system of mononuclear phagocytes without development of pathological changes. This review highlights principal mechanisms responsible for safe removal of immune complexes in primates and humans. Special attention is given to diseases known as "immune complex diseases", when antigen-antibody complexes induce inflammatory reactions. The review considers key experimental works that significantly contributed to current knowledge of etiology and pathogenesis of type III hypersensitivity. Some factors of the development of immune complex syndrome such as level of humoral immune response to antigen, isotype and affinity of forming antibodies, the amount of immune complexes, and the consequences of their interaction with the complement system and Fc-receptors are analyzed based on the molecular mechanisms involved. The review contains a retrospective analysis of the most significant scientific achievements in immune complex pathology investigation within the last 100 years \\\\expert2\\NBO\\Biochemistry\\2009, v.74, p. 469-479.pdf |
S 54 Shmagel, K. V. Steroid hormones: their physiological role and diagnostic value during pregnancy / K. V. Shmagel, V. A. Chereshnev // Uspekhi fiziologicheskikh nauk . - 2004. - Vol.35, №3. - P61-71 Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CORTICOTROPIN -- ESTRIOL -- ESTROGEN Аннотация: Steroid hormones play a key role in the beginning, development and termination of gestation. This reveiw is devoted for physiological effects of estrogens, progesterone, cortisole, ACTH, CRH in various pregnancy events: implantation, fetus development, maternal adaptation and birth initiation. Priority is fixed for estrogens--steroids that vastly increase maternal circulating blood value, induce progesterone action on uterus, regulate fetal "hypothalamic-pituitary-adrenocortical" axis, control free cortisole level in feminine blood. Diagnostic criterions of steroid hormone determination durijng pregnancy are presented. To day unconjugated estriol is the only steroid hormone that implicated in total pregnancy screening programs. Its concentration reduction has been noted in pregnancies with Dawn syndrome, some child enzyme defetcs, intrauterine growth retardation and fetal death incidents |
S 54 Shmagel, K. V. Modern view on immunology of periodontitis / K. V. Shmagel, O. V. Beliaeva , V. A. Chereshnev // Stomatologiia. - 2003. - Vol. 82, № 1. - P61-64 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): ANTIBODY PRODUCTION -- CELLULAR IMMUNITY -- PERIODONTITIS |
I-58 Industrial environment and the immune system [Electronic resource] / V. A. Chereshnev [et al.] // Clinical and Applied Immunology Reviews . - 2001. - Vol. 1, № 3-4. - P147-152. - Bibliogr. : p. 152 (15 ref.) Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ANTHROPOGENIC POLLUTION -- ECOLOGICAL IMMUNOLOGY -- IMMUNE CORRECTION Аннотация: Major issues of the new scientific field of ecological immunology are considered. The principles of carrying out the immunotoxicological examinations are studied by the example of long-term observations from the ecological-immunological monitoring of adults and children from the West Ural, and also by the experiments (field tests) with animals. The concept of secondary ecologically-dependent immune deficient state is formulated, and the means for immune correction, including prevention, therapy and rehabilitation of the immune system alterations, are addressed |
T 10 T cell apoptosis in HIV-infected patients with incomplete immune recovery after antiretroviral therapy [Electronic resource] / E. V. Saidakova, L. B. Korolevskaya, K. V. Shmagel, N. G. Shmagel, V. A. Chereshnev // Doklady Biological Sciences. - 2013. - Vol. 450, № 1. - P189-191. - Библиогр.: с. 191 (5 ref.) Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): ANTIRETROVIRAL THERAPY -- HIV-INFECTED -- T CELL \\\\expert2\\nbo\\Doklady Biological Sciences\\2013. V. 450, N 1. P. 189-191.pdf |
I-70 Investigation of mechanisms of immunological inefficiency of antiretroviral therapy in HIV infection / K. V. Shmagel, N. G. Shmagel, E. G. Saydakova [и др.] // ERA. Net RUS. Brokerage event . - Yekaterinburg, 2011. - С. 34 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): IMMUNOLOGICAL INEFFICIENCY -- ANTIRETROVIRAL THERAPY |
S 51 Several causes for immunological inefficiency of antiretroviral therapy of HIV infection / K. V. Shmagel, N. G. Shmagel, N. Vorobyeva, V. A. Chereshnev // 6 th IAS conference on HIV pathogenesis, treatment and prevention, Roma, Italy, 17-20 July 2011 : abstract. - Roma, 2011. - CDB244 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): IMMUNOLOGICAL INEFFICIENCY -- ANTIRETROVIRAL THERAPY |
K 40 Kevorkov, N. N. Stimulation of antibody production after chest trauma is thymus-dependent / N. N. Kevorkov, V. A. Chereshnev, K. V. Shmagel // Intensive Care Medicine. - 1994. - Vol. 20, № 1 Suppl. - С. 337 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): ANTIBODY PRODUCTION -- CHEST TRAUMA |
T 44 The role of systemic inflammation in the formation of CD4+T cell deficiency in HIV/HCV coinfection / E. V. Saidakova, L. B. Korolevskaya, K. V. Shmagel [et al.] // International Journal of Rheumatic Diseasis. - 2014. - Vol. 17, Suppl. 2. - P17-18 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): INFLAMMATION -- COINFECTION -- CD4+T \\\\expert2\\nbo\\International Journal of Rheumatic Diseases\\2014. V. 17, Suppl. 2. P. 17-18.pdf |
I-60 Influence of hepatitis C virus coinfection on CD4⁺ T cells of HIV-infected patients receiving HAART / K. V. Shmagel, E. V. Saidakova, L. B. Korolevskaya [et al.] // AIDS. - 2014. - Vol. 28, № 16. - P2381-2388. - Bibliogr. : p. 2388 (31 ref.) Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): C VIRUS (HCV -- HIV Аннотация: The effects of hepatitis C virus (HCV) coinfection on immune homeostasis and immune restoration in treated HIV infection are not well understood \\\\Expert2\\NBO\\AIDS\\2014 V 28 N 16 P. 2381-2388.pdf |
L 83 Liver damage and inflammation in HIV/hepatitis C virus coinfection [Text] / K. V. Shmagel, E. V. Saidakova, N. G. Shmagel [et al.] // Глобальное партнерство в борьбе с ВИЧ/СПИДом. Ценна каждая жизнь : тезисы пятой конференции по ВИЧ/СПИДу в Восточной Европе и Центральной Азии. - Москва, 2016. - P278-279 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): HIV/HEPATITIS -- LIVER DAMAGE \\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Тезисы 5 конференции по СПИДУ 2016-Abstracts P. 278-279.pdf |
C 51 Chereshnev, V. A. Regulation disturbance of immune response in combined stress / V. A. Chereshnev, K. V. Shmagel // Constituent Congress International Society for Pathophysiology: abstracts. - Kuopio, 1991. - P173 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): ИММУНИТЕТ -- ИММУНИТЕТ (ИССЛЕДОВАНИЯ) -- СТРЕСС \\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Constituent congress 1991 P. 173.pdf |
E 27 Effect of hepatitis C vIrus coinfection on the content of CD4+ and CD8+ T cell subpopulations in HIV-infected patients receiving antiretroviral therapy / L. B. Korolevskaya, K. V. Shmagel, E. V. Saidakova [et al.] // Bulletin of experimental biology and medicine. - 2016. - Vol. 161, № 2. - P281-283. - Bibliogr. : p. 283 (12 ref.) Рубрики: ЗДРАВООХРАНЕНИЕ--КЛИНИЧЕСКАЯ МЕДИЦИНА Кл.слова (ненормированные): HIV INFECTION -- HCV COINFECTION -- ANTIRETROVIRAL THERAPY -- T CELL SUBPOPULATIONS Аннотация: We studied the effect of hepatitis C virus coinfection on T cell subpopulations in HIV-infected patients receiving antiretroviral therapy. Coinfection with hepatitis C virus was followed by a decrease in the number of naive CD4+ T cells and an increase in the count of central CD8+ memory T cells in these patients. Hepatitis C virus had no effect on the number of CD4+ memory T cells (main target for HIV). This can explain the absence of strong negative effect of hepatitis C virus on the course of HIV infection. \\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2016, v.161, N 2, p. 281-283.pdf |
S 98 Systemic inflammation and liver damage in HIV/hepatitis C virus coinfection / K. V. Shmagel, E. V. Saidakova, N. G. Shmagel [et al.] // HIV Medicine. - 2016. - Vol. 17, № 8. - P581-589. - Bibliogr. : p. 7-9 (40 ref.) Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): ANTIGENS -- HEPATITIS C -- HIV INFECTION \\\\expert2\\NBO\\HIV Medicine\\2016. 1-9.pdf |
C 36 CD8.sup.+ T cell expansion in HIV/HCV coinfection is associated with systemic inflammation / E. V. Saidakova, K. V. Shmagel, L. B. Korolevskaya [et al.] // Doklady Biological Sciences. - 2017. - Vol. 474, № 1. - P126-128 Рубрики: НАУКА. НАУКОВЕДЕНИЕ Кл.слова (ненормированные): HEPATITIS C -- RISK FACTORS -- COMORBIDITY -- RISK FACTORS -- T CELLS -- HEPATITIS C VIRUS Аннотация: High prevalence of non-AIDS-defining illnesses in treated HIV-infected patients is associated with increased peripheral CD8.sup.+ T cell counts. Hepatitis C virus (HCV) coinfection is an additional risk factor for the development of non-AIDS events. We found that, in HIV/HCV coinfection, the increased proportion of CD8.sup.+ T lymphocytes is due to the effector memory and terminal effector T cells gain. Moreover, in these patients, the accumulation of highly differentiated forms of CD8.sup.+ T lymphocytes was associated with increased concentrations of inflammatory indices. \\\\Expert2\\NBO\\Doklady Biological Sciences\\2017 v. 474 p. 126-128.pdf |
I-60 Influens of hepatitis C virus coinfection on CD4+ T cell of HIV-infected patients receiving HAART / K. V. Shmagel, E. V. Saidakova, L. B. Korolevskaya, N. G. Shmagel, V. A. Chereshnev, D. D. Anthony, M. M. Lederman // AIDS. - 2014. - Vol. 28, № 16. - P2382-2388 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ |
U 62 Untreated HCV-coinfection in HIV-infected patients induces additional CD4+ T-lymphocyte deficiency due to mobilization of naive cells into immune response resulting in their regeneration failure / K. V. Shmagel, E. V. Saidakova, L. B. Korolevskaya [et al.] // IAS 2017 : 9th IAS conference on HIV Science : Abstract book. - Paris, 2017. - P241 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ \\\\Expert2\\NBO\\статьи из сборников\\Абстракт_ Париж-2017.pdf |
Lymphopenia-induced proliferation of CD4 T-cells is associated with CD4 T-lymphocyte exhaustion in treated HIV-infected patients / E. V. Saidakova, K. V. Shmagel, L. B. Korolevskaya [et al.] // Indian journal of medical research. - 2018. - Vol. 147, № 4. - P376-383 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ \\\\Expert2\\NBO\\Indian journal of medical research\\2018 Т.12 № 3 С. 233-237.pdf |
H 65 High level of sistemic inflammation in HIV/hepatitis C coinfection is linked to hepatocellular injury / E. V. Saidakova, K. V. Shmagel, L. B. Korolevskaya [et al.] // Tokyo – Moscow International Medical Forum : program & abstract book. - Moscow, 2018. - P73 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ \\\\Expert2\\NBO\\Электрон. библиотека (Отеч.периодика)\\Черешнев В. А\\Tokyo – Moscow International Medical Forum 2018 P.73.pdf |