Главная Новые поступления Описание Шлюз Z39.50

Базы данных


Труды сотрудников Института органического синтеза УрО РАН - результаты поиска

Вид поиска
Каталог книг и продолжающихся изданий
Сводный каталог иностранных периодических изданий, имеющихся в библиотеках УрО РАН
Сводный каталог отечественных периодических изданий, имеющихся в библиотеках УрО РАН
Каталог диссертаций и авторефератов диссертаций УрО РАН
Каталог препринтов УрО РАН (1975 г. - )
Имидж-каталог отечественных книг (до 2010 г.)
Имидж-каталог иностранных книг (до 2010 г.)
Алфавитно-предметный указатель (АПУ) ЦНБ УрО РАН
Публикации об УрО РАН
Изобретения уральских ученых
Интеллектуальная собственность (статьи из периодики)
Нанотехнологии
Демидовские премии
Гибель династии Романовых
История Урала
Личная библиотека С. В. Вонсовского
Книжная коллекция Шубиных
Труды Института высокотемпературной электрохимии УрО РАН
Труды Института истории и археологии УрО РАН
Труды сотрудников Института горного дела УрО РАН
Труды сотрудников Института органического синтеза УрО РАН
Труды сотрудников Института теплофизики УрО РАН
Труды сотрудников Института химии твердого тела УрО РАН
Расплавы
Труды сотрудников ЦНБ УрО РАН
Публикации Черешнева В.А.
Публикации Чарушина В.Н.
Каталог библиотеки ИГД УрО РАН
Каталог библиотеки ИЭРиЖ УрО РАН
Электронная энциклопедия «Дискурсология»
Библиометрия
Область поиска
в найденном
 Найдено в других БД:Публикации Чарушина В.Н. (1)
Формат представления найденных документов:
полныйинформационныйкраткий
Отсортировать найденные документы по:
авторузаглавиюгоду изданиятипу документа
Поисковый запрос: (<.>K=DIASTEREOMERS<.>)
Общее количество найденных документов : 14
Показаны документы с 1 по 10
 1-10    11-14 
1.
Инвентарный номер: нет.
   
   R 35

   
    Regioselective reaction of ortho-piperidinobenzaldehydes with pyrazolone [Electronic resource] / A. Yu. Platonova, E. V. Deeva, O. A. Zimovets, D. V. Shatunova, O. S. Eltsov, P. A. Slepukhin, T. V. Gluchareva, Yu. Yu. Morzherin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 961-964. - Bibliogr. : p. 964 (20 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
TERT-AMINO EFFECT -- PYRAZOLONE -- DIASTEREOMERS
Аннотация: Cyclization of 2 (4 R piperidino)benzaldehydes with 5 methyl 2 phenyl 2,4 dihydro 3H pyrazol 3 one proceeding via tert amino effect mechanism is stereoselective. Relative configu ration of (3R*,4aS*,5R*) 2,3,4,4a,5,6 hexahydro 1H benzo[c]quinolizine was established on the base of NMR spectroscopy data and X ray analysis

\\\\expert2\\NBO\\Russian Chemical Bulletin\\2011, 60 (5), 961-964.pdf
Найти похожие
2.
Инвентарный номер: нет.
   
   A 10

   
    A simple synthesis of the pentacyclic lamellarin skeleton from 3-nitro-2-(trifluoromethyl)-2H-chromenes and 1-methyl(benzyl)-3,4-dihydroisoquinolines / V. Yu. Korotaev, V. Ya. Sosnovskikh, A. Yu. Barkov, P. A. Slepukhin, M. A. Ezhikova, M. I. Kodess, Yu. V. Shklyaev // Tetrahedron. - 2011. - Vol. 67, № 45. - С. 8685-8698
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
LAMELLARIN ALKALOIDS -- ISOQUINOLINE DERIVATIVES -- HETEROCYCLIC SYSTEM
Аннотация: The basic structural framework of lamellarin alkaloids, 8,9-dihydro-6H-chromeno[4?,3?:4,5]pyrrolo[2,1-a]isoquinoline derivatives, has been obtained in good yields via Grob synthesis between 3-nitro-2-(trifluoromethyl)-2H-chromenes and 1-methyl-3,4-dihydroisoquinolines in refluxing isobutanol. In the case of 1-benzyl-3,4-dihydroisoquinolines, a dynamic NMR effect was observed in the 1H and 19F NMR spectra of the products as a result of restricted rotation about the single bond linking the benzene ring and the heterocyclic system. When the reaction was carried out with 3-nitro-2-(trichloromethyl)-2H-chromenes in toluene at room temperature, only Michael adducts, as a mixture of two diastereomers, were isolated.??????--------------------------------------------------------------------------------??

Найти похожие
3.
Инвентарный номер: нет.
   
   R 30

   
    Reaction of alkyl 5,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylates with zinc enolates prepared from zinc and 1-arul-2-bromo-2-phenylethanones, 2 bromoindanone, and 2-bromo-6-methyltetralone [Electronic resource] / V. V. Shchepin, A. E. Korzun, M. I. Vakhrin, P. S. Silaichev, M. A. Ezhikova, M. I. Kodess // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2006. - Vol. 42, № 8. - P1169-1173
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Alkyl 5,5-dimethyl-2-oxo-2,5-dihydrofuran-3-carboxylates react with zinc enolates prepared from 1-aryl-2-bromo-2-phenylethanones, 2-bromo indanone, 2-bromo-6-methyltetralone and zinc with formation of ethyl 4-(2-aryl-2-oxo-1-phenyl-ethyl)-5,5-dimethyl-2-oxotetrahydrofuran-3-carboxylates, alkyl 5,5-dimethyl-2-oxo-4-(1-oxoindan-2-yl)tetrahydrofuran-3-carboxylates, and ethyl 5,5-dimethyl-4-(6-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)-2-oxotetrahydrofuran-3-carboxylates respectively, mainly as single diastereomers

\\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2006, 42 (8), 1169.pdf
Найти похожие
4.
Инвентарный номер: нет.
   

   
    2-Arylpropionyl chlorides in kinetic resolution of racemic 3-methyl-2,3-dihydro-4H-[1,4]benzoxazines [Electronic resource] / E. N. Chulakov, D. A. Gruzdev, G. L. Levit, L. Sh. Sadretdinova, V. P. Krasnov, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 948-954. - Bibliogr. : p. 953-954 (34 ref.)
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
KINETIC RESOLUTION -- ACYL CHLORIDES -- ENANTIOMERS
Аннотация: Kinetic resolution of racemic 3 methyl 2,3 dihydro 4H [1,4]benzoxazines in the reaction with chiral 2 arylpropionyl chloride predominantly yielded R*,R* diastereomers. Ibuprofen acyl chloride as acylating agent was found to be more selective and sensitive to the changes in the reaction temperature as compared to naproxen acyl chloride and 2 phenylpropionyl chloride

\\\\expert2\\NBO\\Russian Chemical Bulletin\\2011, 60 (5), 948-954.pdf
Найти похожие
5.
Инвентарный номер: нет.
   

    Korolyova, M. A.
    Theoretical study of the stereoselectivity in the reaction of 4-haloglutamic acid derivatives with arylamines / M. A. Korolyova, A. Yu. Vigorov, V. P. Krasnov // Russian chemical bulletin. - 2022. - Vol. 71, № 6. - P1135-1142
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: Diastereoselective nucleophilic substitution reaction of halogen in dimethyl (2S,4RS)-4-bromo- and 4-iodo-N-phthaloylglutamates with arylamines was studied within the framework of the electron density functional theory. According to calculations, the stereoselectivity of the substitution reaction with respect to (2S,4S)-isomers of 4-arylamino derivatives is determined not only by the steric hindrances in the transition state leading to minor (2S,4R)-diastereomers, but also by the stabilization of the corresponding initial reagents complex due to stacking interactions of the aromatic fragments of reagents.

Найти похожие
6.
Инвентарный номер: нет.
   

   
    Synthesis of heterocycles on the base of trifluoroacetoacetate, methyl ketones and diamines / M. V. Goryaeva, S. O. Kushch, Y. V. Burgart, V. I. Saloutin // AIP conference proceedings. - 2022. - Vol. 2390. - Ст. 020021
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
TRIFLUOROACETOACETATE -- METHYL KETONES -- DIAMINES
Аннотация: The three-component cyclization of ethyl trifluoroacetoacetate and 2-aminoethanol with 3-methyl-2-butanone in hexahydrooxazolo[3,2-a]pyridin-5-ones was studied. The reaction leads to a mixture of cis- and trans- diastereomers, the structures of which were investigated using 1H, 19F, 13C NMR spectroscopy.

Найти похожие
7.
Инвентарный номер: нет.
   
   S 83

   
    Stereochemical aspects in the synthesis of novel N-(purin-6-yl)dipeptides as potential antimycobacterial agents / V. V. Musiyak, I. A. Nizova, E. N. Chulakov [et al.] // Amino Acids. - 2021. - Vol. 53, № 3. - P407-415
ББК Г
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
DIPEPTIDES -- RACEMIZATION -- PURINE -- COUPLING -- NUCLEOPHILIC SUBSTITUTION -- ANTIMYCOBACTERIAL ACTIVITY
Аннотация: The synthesis of purine conjugates with natural amino acids is one of the promising directions in search for novel therapeutic agents, including antimycobacterial agents. The purpose of this study was to synthesize N-(purin-6-yl)dipeptides containing the terminal fragment of (S)-glutamic acid. To obtain the target compounds, two synthetic routes were tested. The first of them is based on coupling of N-(purin-6-yl)-(S)-amino acids to dimethyl (S)-glutamate in the presence of carbodiimide coupling agent followed by the removal of ester groups. However, it turned out that this coupling process was accompanied by racemization of the chiral center of N-(purin-6-yl)-α-amino acids and in all cases led to mixtures of (S,S)- and (R,S)diastereomers (6:4). Individual (S,S)-diastereomers were obtained using an alternative approach based on the nucleophilic substitution of chlorine in 6-chloropurine or 2-amino-6-chloropurine with corresponding dipeptides as nucleophiles. The enantiomeric purity of the target compounds was confirmed by chiral HPLC. To test the assumption that racemization of the chiral center of N-(purin-6-yl)-α-amino acids occurs with the participation of nitrogen atoms of the imidazole ring via the stage of formation of a chirally labile intermediate, we obtained such structural analogs of N-(purin-6-yl)-(S)-alanine as N-(9-benzylpurin-6-yl)-(S)-alanine and N-(7-deazapurin-6-yl)-(S)-alanine. It was found that coupling of these compounds to dimethyl (S)-glutamate was also accompanied by racemization. This indicates that the imidazole fragment does not play a crucial role in this process. When testing the antimycobacterial activity of some of the obtained compounds, conjugates with moderate activity against the laboratory Mycobacterium tuberculosis H37Rv strain (MIC 3.1–6.25 μg/mL) were identified.

Найти похожие
8.
Инвентарный номер: нет.
   
   F 94

   
    From oxides of internal perfluoroolefins to fluorocontaining camphor thiazolinylhydrazones [Text] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, K. A. Lyssenko, M. Yu. Antipin, V. I. Saloutin, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2003. - Vol. 120, № 1. - P41-47
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The reaction of oxides of internal trans- and cis-perfluoroolefins with (1S, 4S)- or racemic camphor thiosemicarbazone leads to the formation of trans- and cis-isomers of (1S, 4S)- or racemic camphor 5?-fluoro-4?-hydroxy-4?,5?-di(perfluoroalkyl)-1?,3?-thiazolinyl-2?-hydrazones, respectively. Unsymmetrical dodecafluoro-2,3-epoxyhexane yields a mixture of regioisomeric hydrazones. The molecular structure of the trans-isomer of (1S, 4S)-camphor 5?-fluoro-4?-hydroxy-4?,5?-bis(trifluoromethyl)-1?,3?-thiazolinyl-2?-hydrazone has been established by X-ray crystallography. The quite rare example of cocrystallization of two diastereomers of the latter in homochiral crystal (sp. group P21) has been revealed????

Найти похожие
9.
Инвентарный номер: нет.
   
   D 62

   
    Direct diastereoselective addition of l-menthol to activated 1,2,4-triazin-5(4H)-one [Text] / O. N. Chupakhin, G. V. Zyryanov, V. L. Rusinov, V. P. Krasnov, G. L. Levit, M. A. Koroleva, M. I. Kodess // Tetrahedron Letters. - 2001. - Vol. 42, № 12. - P2393-2395
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: For the first time in a triazine series it has been found that addition of a chiral O-nucleophile, l-menthol, to the C6-unsubstituted atom of 3-phenyl-1,2,4-triazin-5(4H)-one 1 activated by aliphatic acid anhydrides proceeds diastereoselectively to form a mixture of 1-acyl-6-[(1?R,3?R,4?S)-menthyl-3?)]-3-phenyl-(6S)-1,6-dihydro-1,2,4-triazin-5(4H)-ones 2 and 1-acyl-6-[(1?R,3?R,4?S)-menthyl-3?)]-3-phenyl-(6R)-1,6-dihydro-1,2,4-triazin-5(4H)-ones 3 in which the diastereomers 2 predominate. The diastereoselectivity of the process improves as the size of the N1-acyl substituent increases????

Найти похожие
10.
Инвентарный номер: нет.
   
   S 98

   
    Synthesis of 4-amino derivatives of 5-oxoproline [Text] / V. P. Krasnov, A. Yu. Vigorov, I. A. Nizova, T. V. Matveeva, A. N. Grishakov, I. V. Bazhov, A. A. Tumashov, M. A. Ezhikova, M. I. Kodess // European Journal of Organic Chemistry. - 2007. - № 25. - P4257-4266
ББК 54
Рубрики: ХИМИЧЕСКИЕ НАУКИ
Аннотация: The possibility of obtaining the stereoisomeric derivatives of 5-oxoproline and glutamic acid with a tertiary amino group at C-4, using the nucleophilic substitution of bromine in dimethyl (2S,4RS)-4-bromo-N-phthaloylglutamate with secondary amines followed by resolution of diastereomers and removal of protecting groups has been studied. We have shown that the reaction with arylamines results in optically pure 5-oxoproline derivatives in high yields. In the case of more basic amines, the reaction is accompanied by racemization, and the target products can be isolated only as diastereomeric racemates.

Найти похожие
 1-10    11-14 
 
Описание базы данных
Стандартный
По словарю
Расширенный
ГРНТИ-навигатор
Статистика обращений

Сиглы отделов ЦНБ УрО РАН


  бр.ф. - Бронированный фонд

  бф - Научно-библиографический отдел

  БХЛ - Фонд художественной литературы

  ИИиА -Фонд исторической литературы в ЦНБ УрО РАН

  ИМЕТ -Отдел ЦНБ в Институте металлургии УрО РАН

  кх - Отдел фондов (книгохранениe)

  МБА - Межбиблиотечный абонемент

  мф - Методический фонд

  ок - Отдел научной каталогизации

  оку - Отдел комплектования и учета

  орф - Обменно-резервный фонд

  пф - Читальный зал деловой и патентной информации

  рк - Фонд редкой книги

  ч/з - Главный читальный зал

  эр - Зал электронных ресурсов

  

Сиглы библиотек институтов и НЦ УрО РАН
© Международная Ассоциация пользователей и разработчиков электронных библиотек и новых информационных технологий
(Ассоциация ЭБНИТ)
Яндекс.Метрика