Z 99 [4+2]Cycloadition reactions of substituted 1,2,4,5-tetrazines with alkenes [Text] : доклад, тезисы доклада / R. I. Ishmetova, G. L. Rusinov, N. I. Latosh, N. K. Ignatenko // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P69 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
L 36 Latosh, N. I. Nucleophilic Substitution Reactions in the Series of (3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazines [Text] : доклад, тезисы доклада / N. I. Latosh, G. L. Rusinov, E. G. Polovinko // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P90 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
G 17 Ganebnuikh, I. N. Synthesis of 3-(3,5-dimethyl-4-x-pyrazolyl-1)triazolo-[4,3-b]-1,2,4,5-tetrazines and their Reactions with N-nucleophiles [Text] : доклад, тезисы доклада / I. N. Ganebnuikh, G. L. Rusinov, O. N. Chupakhin // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P64 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
M 78 Modeling of 1,2,4,5-tetrazine complexes with organic amines [Electronic resource] / M. A. Grishina, V. A. Potemkin, E. V. Bartashevich, A. N. Sinyaev, G. L. Rusinov, N. I. Latosh, I. N. Ganebnuikh, O. V. Koryakova, R. I. Ishmetova // Journal of Structural Chemistry. - 2006. - Vol. 47, № 6. - P1155-1160 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Journal of Structural Chemistry\\2006, V. 47, N 6, p.1155.pdf |
H 62 Heteroaryl displacement in 3,6-disubstituted 1,2,4,5-tetrazines with anhydro bases of N-methylquinaldiniums [Text] / G. L. Rusinov, R. I. Ishmetova, I. N. Ganebnuikh, O. N. Chupakhin // Heterocyclic Communications. - 2006. - Vol. 12, № 2. - P99-102 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
K 80 Kozhevnikov, D. N. Triazines, tetrazines and fused ring polyaza systems [Text] / D. N. Kozhevnikov, V. N. Kozhevnikov // Progress in Heterocyclic Chemistry. - 2009. - Vol. 21. - P435-454. - Bibliogr. : p. 450-454
|
Z 99 [4+2]-Cycloaddition of 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines with alkenes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, N. I. Latosh, I. N. Ganebnuikh, O. N. Chupakhin, V. A. Potemkin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2000. - Vol. 49, № 2. - P355-362 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A number of 1,4-dihydropyridazines and pyridazines were prepared by the Diels-Alder reaction with an inverse electron demand from cyclic heterodiene systems, 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines, and some enamines as well as from 4-vinylpyridine, butyl vinyl ether, phenylacetylene, and acrylamide. The reaction of 3,6-bis(3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazine with styrene afforded 4,5-dihydropyridazine, which was readily oxidized by atmospheric oxygen to form the corresponding pyridazine. Electron-withdrawing substituents (Br or Cl) in the pyrazole rings accelerate [4+2]-cycloaddition. When heated, 1,4-dihydropyridazines, which were synthesized from tetrazines and enamines, eliminated amine to give pyridazines. The reactivities of tetrazines were evaluated by quantum-chemical methods. \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2000, 49 (2), 355.pdf |
S 98 Synthesis of 1,2,4,5-tetrazines, symmetrically and unsymmetrically 3,6-disubstituted by N-nucleophiles [Electronic resource] / G. L. Rusinov, N. I. Latosh, I. N. Ganebnuikh, R. I. Ishmetova, N. K. Ignatenko, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2006. - Vol. 42, № 5. - P757-765 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 6-R-3-(3,5-Dimethylpyrazol-1-yl)-1,2,4,5-tetrazines with aliphatic, cycloaliphatic, and aromatic amines, and also with NH-heterocycles undergo a nucleophilic substitution of the dimethylpyrazole moiety yielding symmetrically and unsymmetrically substituted 1,2,4,5-tetrazines. In the 3,6-diimidazolyl-and 3,6-dibenzotriazolyl derivatives reactions of nucleophilic substitution of the heterocyclic moiety also occur. In some cases an ipsosubstitution of amino, hydrazino, and azido groups is observed. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2006, 42 (5), 757.pdf |
S 98 Synthesis and structures of pyridoannelated 1,2,3,4-tetrazine 1,3-dioxides [Electronic resource] / V. A. Tartakovsky, I. E. Filatov, A. M. Churakov, S. L. Ioffe, Yu. A. Strelenko, V. S. Kuzmin, G. L. Rusinov, K. I. Pashkevich // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2004. - Vol. 53, № 11. - P2577-2583 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Treatment of 2- and 4-amino-3-(tert-butyl-NNO-azoxy)pyridines with nitrating agents (N2O5or NO2BF4) afforded the first representatives of pyridoannelated 1,2,3,4-tetrazine di-N-oxides, viz., pyrido[2,3-e][1,2,3,4]tetrazine 1,3-dioxide (9), 7-nitropyrido[2,3-e][1,2,3,4]tetrazine 1,3-dioxide (10), and pyrido[3,4-e][1,2,3,4]tetrazine 2,4-dioxide (11). These compounds were studied by 1H, 13C, and 14N NMR spectroscopy. The 1:1 complex of compound 10 with benzene was studied by X-ray diffraction analysis. \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2004, 53 (11), 2577.pdf |
R 44 Replacement of dimethylpyrazolyl group in 1,2,4,5-tetrazines by aliphatic alcohols and water [Electronic resource] / R. I. Ishmetova, N. I. Latosh, I. N. Ganebnuikh, N. K. Ignatenko, S. G. Tolshchina, G. L. Rusinov // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2009. - Vol. 45, № 7. - P1102-1107 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reactions of 3,6-bis(4-R-3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazines and 3-amino-6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazines with aliphatic alcohols and water in the presence of a base involved replacement of the dimethylpyrazolyl group and resulted in the formation of mono- and dialkoxy-1,2,4,5-tetrazines and 6-substituted 3-hydroxy-1,2,4,5-tetrazines. Dissociation constants of the latter were determined by potentiometric titration. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2009, 45 (7), 1102.pdf |
K 80 Kozhevnikov, D. N. Triazines, Tetrazines and Fused Ring Polyaza Systems [Text] / D. N. Kozhevnikov, A. M. Prokhorov // Progress in Heterocyclic Chemistry. - 2011. - Vol. 22. - P427-447 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
S 98 Synthesis, structures, and magnetic properties of crystals of dinuclear copper(II) and cobalt(II) complexes with 3-(3,5-dimethylpyrazol-1-yl)-6-R-1,2,4,5-tetrazines [Electronic resource] / E. V. Cherdantseva, D. V. Starichenko, P. A. Slepukhin, R. I. Ishmetova, Yu. N. Shvachko, A. V. Korolev, G. L. Rusinov, V. V. Ustinov, A. I. Matern, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 4. - P717-723 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): DINUCLEAR COMPLEXES -- SPIN MAGNETISM -- TETRAZINES Аннотация: Dinuclear complexes of CuII with 3-(3,5-dimethylpyrazol-1-yl)-6-(2-hydroxyethylami-no)-1,2,4,5-tetrazine (1) and CoII with 3-(3,5-dimethylpyrazol-1-yl)-6-(piperidin-1-yl)-1,2,4,5- tetrazine (2) were synthesized and structurally characterized, and the magnetic (SQUID) and resonance (EPR) properties of van der Waals crystals based on these complexes were studied. Unusual behavior of the effective magnetic moment ?eff(T) is observed at T < 60 K. A nonmonotonic increase in eff() for 1 (s~6 %) and a 20% reduction of eff for 2 have a common origin and are due to the influence of spin-orbital coupling on the character of the splitting between the t2g and eg levels of the central ion. Distortions of the coordination site “switch on” a positive (1) or negative (2) contribution of the orbital magnetic moment near 6 K. Irreversible temperature behavior of eff(T) in the heating and cooling regimes in the vicinity of 60 K suggests that the character of structural distortions and the magnetic properties are related to ligand geometry. This factor plays a significant role in crystal engineering of magnetoactive structures with polynitrogen ligands \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2010, 59 (4), 717-723.pdf |
Z 99 [4+2] Cycloaddition reactions of 1,2,4,5-tetrazines with allylcarboranes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, S. G. Tolshchina, N. K. Ignatenko, I. N. Ganebnuikh, P. A. Slepukhin, V. A. Ol'shevskaya, V. N. Kalinin, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P116-121 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ALLYLCARBORANES -- PYRIDAZINES -- [4+2] CYCLOADDITION???? Аннотация: The [4+2] cycloaddition reactions of 3,6-disubstituted 1,2,4,5-tetrazines with 9-allyl-1,7-,9-allyl-1,2-dicarba-closo-dodecaboranes and 1-allyl-2-isopropyl-1,2-dicarba-closo-dodecab-orane have been studied. The pyridazines containing carborane cage have been synthesized for the first time \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2009, 59 (1), 116-121.pdf |
C 45 Changes in the vibrational characteristics of substituted 1,2,4,5-tetrazines after complexation with 1,2,3-benzotriazole: A theoretical study [Electronic resource] / N. N. Ivshina, E. V. Bartashevich, V. A. Potemkin, M. A. Grishina, R. I. Ishmetova, G. L. Rusinov, N. I. Latosh, P. A. Slepukhin, V. N. Charushin // Journal of Structural Chemistry. - 2009. - Vol. 50, № 6. - P1053-1058 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The complexation of 3,6-substituted 1,2,4,5-tetrazines with benzotriazole was studied theoretically based on the vibrational spectra. For model complexes, the energy was minimized by the geometrical parameters, and the spectral characteristics were calculated by the PM3 method. The shift of the bond vibration frequencies of the atoms involved in complexation after the formation of different various intermolecular contacts was determined. This made it possible to determine the type of intermolecular interaction and suggest the structures of the complexes \\\\Expert2\\nbo\\Journal of Structural Chemistry\\2009, V. 50, N 6, p.1053.pdf |
S 98 Synthesis of 5-trifluoromethylpyrazol-1-yl-substituted 1,2,4,5-tetrazines [Electronic resource] / S. G. Tolshchina, N. K. Ignatenko, P. A. Slepukhin, R. I. Ishmetova, G. L. Rusinov // Chemistry of Heterocyclic Compounds. - 2010. - Vol. 46, № 6. - P691-698 : рис., табл. Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 5-HYDROXY-5-TRIFLUOROMETHYLPYRAZOLINES -- 1,2,4,5-TETRAZINES -- 1,1,1-TRIFLUORO-2,4-PENTANEDIONE Аннотация: Previously unknown products of the cyclocondensation of 1,1,1-trifluoro-2,4-pentanedione with triaminoguanidine and hydrazine derivatives of 1,2,4,5-tetrazine have been obtained. 5-Hydroxy-5-trifluoromethylpyrazoline substituents formed on the tetrazine ring were dehydrated under the action of trifluoroacetic anhydride. A comparison has been carried out of the reactivity of 5-trifluoromethylpyrazolyl-substituted 1,2,4,5-tetrazines and their unfluorinated analogs in nucleophilic substitution and [4 + 2] cycloaddition reactions \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2010, v.46, N 6, p.691-698.pdf |
O-56 On the Composition of Copper(II), Cobalt(II), and Nickel(II) Complexes with Some 3,6-Disubstituted 1,2,4,5-Tetrazines [Electronic resource] / E. V. Cherdantseva, A. V. Nesterova, A. I. Matern, L. Yu. Buldakova, M. Yu. Yanchenko, R. I. Ishmetova, G. L. Rusinov // Russian Journal of General Chemistry. - 2010. - Vol. 80, № 9. - P1860-1863 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): COPPER -- COBALT -- NICKEL -- TETRAZINES Аннотация: Complex formation in the systems containing copper(II), cobalt(II) and nickel(II) ions (M) and 3(3,5-dimethylpyrazol-1-yl)-6-R-1,2,4,5-tetrazines (R = 2-hydroxyethylamino, piperidino) (L) was studied by voltammetry and spectrophotometry. Cu(II), Co(II) and Ni(II) were found to form complex compounds with derivatives of 1,2,4,5-tetrazine with the ratio of the components M:L = 1:1. The complex stability constants \\\\Expert2\\nbo\\Russian Journal of General Chemistry\\2010, V. 80, N 9, p.1860-1863.pdf |
R 30 Reactions of 3,6-bis(3,5-dimethyl-4-r-pyrazol-1-yl)-1,2,4,5-tetrazines with indole and 1,3,3-trimethyl-2-methyleneindoline [Text] / R. I. Ishmetova, N. K. Ignatenko, I. N. Ganebnuikh, S. G. Tolshchina, P. A. Slepukhin, G. L. Rusinov // Heterocycles. - 2011. - Vol. 83, № 6. - P1363-1370 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: It has been found that 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines react with indole and 1,3,3-trimethyl-2-methyleneindoline to give pyridazines as [4+2]cycloaddition products. 1,3,3-Trimethyl-2-methyleneindoline has been shown to act as C-nucleophile in the substitution of pyrazolyl group as well as in the reactions of tetrazine ring expansion in [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives |
U 62 Unusual Expansion of the 1,2,4,5-Tetrazine Ring in [1,2,4]Triazolo[4,3-b]-[1,2,4,5]tetrazines Leading to [1,2,4,6]Tetrazepine Systems [Text] / I. N. Ganebnuikh, S. G. Tolshchina, R. I. Ishmetova, N. K. Ignatenko, P. A. Slepukhin, G. L. Rusinov, V. N. Charushin // European Journal of Organic Chemistry. - 2011. - № 12. - P2309-2318. - Bibliogr. : p. 2318 (22 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Expansion of the tetrazine ring has first been found to occur when [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazines were allowed to react with CH-active compounds in acetonitrile in the presence of triethylamine to give the unexpected series of 8,9-dihydro-7H-[1,2,4]-triazolo[4,3-b][1,2,4,6] tetrazepine derivatives \\\\Expert2\\nbo\\European Journal of Organic Chemistry\\2011, p.2309.pdf |
P 93 Prokhorov, A. M. Triazines, Tetrazines, and Fused Ring Polyaza Systems / A. M. Prokhorov, D. N. Kozhevnikov // Progress in Heterocyclic Chemistry. - 2011. - Vol. 23. - С. 403-425 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,2,3-TRIAZINES -- 1,2,4-TRIAZINES -- 1,3,5-TRIAZINES -- TETRAZINES -- PURINES Аннотация: The review covers work published in the calendar year 2010. Novel reaction chemistry and new ring synthetic methods for 1,2,3-triazines, 1,2,4-triazines, 1,3,5-triazines, tetrazines, and purines are reviewed |
R 30 Reactions of 1,2,4,5-tetrazines with S-nuc / S. G. Tolshchina, R. I. Ishmetova, N. K. Ignatenko, A. V. Korotina, I. N. Ganebnuikh, V. A. Ol'shevskaya, V. N. Kalinin, G. L. Rusinov // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 985-991 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,2,4,5-TETRAZINES -- HETEROCYCLIC LEAVING GROUPS -- TETRAZINES Аннотация: The reactions of 3,6-disubstituted and azoloannulated 1,2,4,5-tetrazines containing heterocyclic leaving groups with S-nucleophiles were studied. The methods of introduction of functionalized thiols, including thiol derivatives of 1,7- and 1,2-dicarba-closo-dodecaboranes, into the tetrazine ring were developed. It was established for the first time that, instead of replacement of a leaving group in the tetrazine ring, the attack of S-nucleophile at the unsubstituted carbon atom occurs in the case of imidazo[1,2-b][1,2,4,5]tetrazines to form previously unknown products of nucleophilic substitution of the hydrogen atom \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2011, 60 (5), 985-991.pdf |