G 17 Ganebnuikh, I. N. Synthesis of 3-(3,5-dimethyl-4-x-pyrazolyl-1)triazolo-[4,3-b]-1,2,4,5-tetrazines and their Reactions with N-nucleophiles [Text] : доклад, тезисы доклада / I. N. Ganebnuikh, G. L. Rusinov, O. N. Chupakhin // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P64 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
M 78 Modeling of 1,2,4,5-tetrazine complexes with organic amines [Electronic resource] / M. A. Grishina, V. A. Potemkin, E. V. Bartashevich, A. N. Sinyaev, G. L. Rusinov, N. I. Latosh, I. N. Ganebnuikh, O. V. Koryakova, R. I. Ishmetova // Journal of Structural Chemistry. - 2006. - Vol. 47, № 6. - P1155-1160 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Journal of Structural Chemistry\\2006, V. 47, N 6, p.1155.pdf |
H 62 Heteroaryl displacement in 3,6-disubstituted 1,2,4,5-tetrazines with anhydro bases of N-methylquinaldiniums [Text] / G. L. Rusinov, R. I. Ishmetova, I. N. Ganebnuikh, O. N. Chupakhin // Heterocyclic Communications. - 2006. - Vol. 12, № 2. - P99-102 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
S 98 Synthesis and tuberculostatic activity of some substituted amino acid methyl esters with sym-tetrazine moieties [Electronic resource] / G. L. Rusinov, N. I. Latosh, R. I. Ishmetova, M. A. Kravchenko, I. N. Ganebnuikh, V. A. Sokolov, O. N. Chupakhin // Pharmaceutical Chemistry Journal. - 2005. - Vol. 39, № 1. - P8-10 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Expert2\\nbo\\Pharmaceutical Chemistry Journal\\2005, 39 (1), 8.pdf |
N 57 Ni(II)-Mediated nitrosation of oximes bearing an alfa-CH2 group [Electronic resource] / A. V. Makarycheva-Mikhailova, P. V. Gushchin, M. N. Kopylovich, I. N. Ganebnuikh, V. N. Charushin, M. P. Haukka, J. L. Armando , V. Yu. Kukushkin // Inorganic Chemistry Communications. - 2006. - Vol. 9, № 8. - P869-871 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Heating of NiCl2 · 6H2O with 10-fold excess of an oxime having an CH2 group (1–4) at 100 °C for 1 day in air leads to the formation of the dioxime/ato complexes [Ni(dioxime/ato)2] (5–8) formed due to a novel type of metal-mediated nitrosation. Compounds 5–8 were characterized by elemental analyses, FAB (5–7) or APCI (8) mass-spectrometry, IR, 1H and 13C{1H} spectroscopies (for 8), and X-ray structural study has been performed for 5 and 8; the corresponding ketones (9–12) were identified by LC–MS. \\\\Expert2\\nbo\\Inorganic Chemistry Communications\\2006, v.9, p.869.pdf |
A 10 A new approach to incorporate the carboranyl fragment into 2,5-diazabicyclo[2.2.2]oct-2-enes [Electronic resource] / G. L. Rusinov, E. V. Verbitskiy, P. A. Slepukhin, O. N. Zabelina, I. N. Ganebnuikh, V. N. Kalinin, V. A. Ol'shevskaya // Mendeleev Communications. - 2009. - Vol. 19, № 5. - P243-245 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 5-(Het)aryl-2,3-dicyano-1-ethylpyrazinium salts have been established to react with 9-allyl-ortho- and 9-allyl-meta-carboranes in the presence of sodium iodide into carboranylmethyl derivatives of 2,5-diazabicyclo[2.2.2]oct-2-ene \\\\Expert2\\nbo\\Mendeleev Communications\\2009, v.19, p.243.pdf |
R 32 Reduction of (2S,4S)-4-amino-5-oxoproline derivatives using borane complexes [Text] : доклад, тезисы доклада / A. Yu. Vigorov, I. A. Nizova, L. Sh. Sadretdinova, G. L. Levit, I. N. Ganebnuikh, M. A. Ezhikova, M. I. Kodess // Fifth International Conference on Organic Chemistry for young Scientists (InterYCOS-2009) "Universities Contribution in the Organic Chemistry Progress", devoted to the 175 th anniversary of D.I.Mendeleevs birthday and 80th anniversary of the Chemistry department of St. Petersburg State University foundation, Saint-Petersburg, 22-25 june 2009 : abstr. - СПб., 2009. - P39 (1-07). - Bibliogr. : p. 40 (7 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ |
Z 99 [4+2]-Cycloaddition of 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines with alkenes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, N. I. Latosh, I. N. Ganebnuikh, O. N. Chupakhin, V. A. Potemkin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2000. - Vol. 49, № 2. - P355-362 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A number of 1,4-dihydropyridazines and pyridazines were prepared by the Diels-Alder reaction with an inverse electron demand from cyclic heterodiene systems, 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines, and some enamines as well as from 4-vinylpyridine, butyl vinyl ether, phenylacetylene, and acrylamide. The reaction of 3,6-bis(3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazine with styrene afforded 4,5-dihydropyridazine, which was readily oxidized by atmospheric oxygen to form the corresponding pyridazine. Electron-withdrawing substituents (Br or Cl) in the pyrazole rings accelerate [4+2]-cycloaddition. When heated, 1,4-dihydropyridazines, which were synthesized from tetrazines and enamines, eliminated amine to give pyridazines. The reactivities of tetrazines were evaluated by quantum-chemical methods. \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2000, 49 (2), 355.pdf |
S 98 Synthesis of 1,2,4,5-tetrazines, symmetrically and unsymmetrically 3,6-disubstituted by N-nucleophiles [Electronic resource] / G. L. Rusinov, N. I. Latosh, I. N. Ganebnuikh, R. I. Ishmetova, N. K. Ignatenko, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2006. - Vol. 42, № 5. - P757-765 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 6-R-3-(3,5-Dimethylpyrazol-1-yl)-1,2,4,5-tetrazines with aliphatic, cycloaliphatic, and aromatic amines, and also with NH-heterocycles undergo a nucleophilic substitution of the dimethylpyrazole moiety yielding symmetrically and unsymmetrically substituted 1,2,4,5-tetrazines. In the 3,6-diimidazolyl-and 3,6-dibenzotriazolyl derivatives reactions of nucleophilic substitution of the heterocyclic moiety also occur. In some cases an ipsosubstitution of amino, hydrazino, and azido groups is observed. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2006, 42 (5), 757.pdf |
U 52 Unexpected products in the reactions of s-tetrazine hydrazones with enamines [Text] / G. L. Rusinov, R. I. Ishmetova, I. N. Ganebnuikh, O. N. Chupakhin, G. G. Aleksandrov, I. A. Litvinov, D. B. Krivolapov // Heterocyclic communications. - 2003. - Vol. 9, № 1. - P39-44 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: For the first time in the reactions of some 1,2,4,5-tetrazine hydrazones with enamines in addition to the expected products of Carbony-Lindsey reaction the unusual addition and cyclization products at cyclic and exocyclic nitrogen atom of tetrazine ring have been isolated. |
R 44 Replacement of dimethylpyrazolyl group in 1,2,4,5-tetrazines by aliphatic alcohols and water [Electronic resource] / R. I. Ishmetova, N. I. Latosh, I. N. Ganebnuikh, N. K. Ignatenko, S. G. Tolshchina, G. L. Rusinov // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2009. - Vol. 45, № 7. - P1102-1107 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reactions of 3,6-bis(4-R-3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazines and 3-amino-6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazines with aliphatic alcohols and water in the presence of a base involved replacement of the dimethylpyrazolyl group and resulted in the formation of mono- and dialkoxy-1,2,4,5-tetrazines and 6-substituted 3-hydroxy-1,2,4,5-tetrazines. Dissociation constants of the latter were determined by potentiometric titration. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2009, 45 (7), 1102.pdf |
Z 99 [4+2] Cycloaddition reactions of 1,2,4,5-tetrazines with allylcarboranes [Electronic resource] / G. L. Rusinov, R. I. Ishmetova, S. G. Tolshchina, N. K. Ignatenko, I. N. Ganebnuikh, P. A. Slepukhin, V. A. Ol'shevskaya, V. N. Kalinin, V. N. Charushin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 1. - P116-121 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ALLYLCARBORANES -- PYRIDAZINES -- [4+2] CYCLOADDITION???? Аннотация: The [4+2] cycloaddition reactions of 3,6-disubstituted 1,2,4,5-tetrazines with 9-allyl-1,7-,9-allyl-1,2-dicarba-closo-dodecaboranes and 1-allyl-2-isopropyl-1,2-dicarba-closo-dodecab-orane have been studied. The pyridazines containing carborane cage have been synthesized for the first time \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2009, 59 (1), 116-121.pdf |
C 74 Composition, structure, and properties of pharmacologically active silicon dimethylglycerolates [Electronic resource] / T. G. Khonina, E. Yu. Larchenko, E. V. Shadrina, I. N. Ganebnuikh, A. A. Boyko, E. G. Matochkina, M. I. Kodess, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2010. - Vol. 59, № 12. - P2230-2235. - Bibliogr. : p. 2235 (13 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 1H and 29Si NMR spectroscopy showed that the product of the reaction of dimethyldiethoxysilane with glycerol in the molar ratio 1: 2 is an equilibrium mixture of dimethyldiglyceroxysilane and low-molecular-weight condensation products. The change of viscosity of silicon dimethylglycerolates, synthesized using different excesses of glycerol, versus time was studied by viscosimetry. Composition of products of hydrolysis and condensation of silicon dimethylglycerolates is determined by their concentration in the starting aqueous solutions \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2010, 59 (12), 2230-2235.pdf |
R 30 Reactions of 3,6-bis(3,5-dimethyl-4-r-pyrazol-1-yl)-1,2,4,5-tetrazines with indole and 1,3,3-trimethyl-2-methyleneindoline [Text] / R. I. Ishmetova, N. K. Ignatenko, I. N. Ganebnuikh, S. G. Tolshchina, P. A. Slepukhin, G. L. Rusinov // Heterocycles. - 2011. - Vol. 83, № 6. - P1363-1370 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: It has been found that 3,6-bis(3,5-dimethyl-4-R-pyrazol-1-yl)-1,2,4,5-tetrazines react with indole and 1,3,3-trimethyl-2-methyleneindoline to give pyridazines as [4+2]cycloaddition products. 1,3,3-Trimethyl-2-methyleneindoline has been shown to act as C-nucleophile in the substitution of pyrazolyl group as well as in the reactions of tetrazine ring expansion in [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazine derivatives |
U 62 Unusual Expansion of the 1,2,4,5-Tetrazine Ring in [1,2,4]Triazolo[4,3-b]-[1,2,4,5]tetrazines Leading to [1,2,4,6]Tetrazepine Systems [Text] / I. N. Ganebnuikh, S. G. Tolshchina, R. I. Ishmetova, N. K. Ignatenko, P. A. Slepukhin, G. L. Rusinov, V. N. Charushin // European Journal of Organic Chemistry. - 2011. - № 12. - P2309-2318. - Bibliogr. : p. 2318 (22 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Expansion of the tetrazine ring has first been found to occur when [1,2,4]triazolo[4,3-b][1,2,4,5]tetrazines were allowed to react with CH-active compounds in acetonitrile in the presence of triethylamine to give the unexpected series of 8,9-dihydro-7H-[1,2,4]-triazolo[4,3-b][1,2,4,6] tetrazepine derivatives \\\\Expert2\\nbo\\European Journal of Organic Chemistry\\2011, p.2309.pdf |
C 51 Chemoselectivity in the Reduction of (2S,4S)-4-Amino-5-oxoproline Derivatives with Borane Complexes [Text] / A. Yu. Vigorov, I. A. Nizova, L. Sh. Sadretdinova, M. A. Ezhikova, M. I. Kodess, I. N. Ganebnuikh, V. P. Krasnov // European Journal of Organic Chemistry. - 2011. - № 13. - P2562-2569. - Bibliogr. : p. 2569 (21 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Reduction of the carbonyl groups in N-protected (2S,4S)-4-amino- 5-oxo-1-phenylprolinates with BH(3) complexes resulted in (2S,4S)-4-aminoproline or (2S,4S)-4-aminoprolinol derivatives depending on the reaction conditions and the type of protecting groups used |
S 98 Synthesis of the (2S,4S)-stereoisomers of 4-(indol-1-yl) and 4-arylamino derivatives of 5-oxoproline, proline, and 2-hydroxymethylpyrrolidine / A. Yu. Vigorov, I. A. Nizova, K. E. Shalunova, A. N. Grishakov, L. Sh. Sadretdinova, I. N. Ganebnuikh, M. A. Ezhikova, M. I. Kodess // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 873-881 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 4-AMINOPROLINE -- 4-AMINOPROLINE -- INDOLE Аннотация: Nucleophilic substitution of the halogen atom in dimethyl (S)-4-bromoglutamate followed by removal of the protecting groups and closure of a lactam ring afforded (2S,4S)-4-(indolin-1-yl)-5-oxoproline. The indoline fragment was oxidized into the indole fragment to give (2S,4S)-4-(indol-1-yl)-5-oxoproline; reduction of the carbonyl groups with BH3 yielded (2S,4S)-4-(indol-1-yl)prolines and (2S,4S)-2-hydroxymethyl-4-(indol-1-yl)pyrrolidines. Reduction of (2S,4S)-4-arylamino-5-oxoprolines with BH3 to the corresponding (2S,4S)-4-arylaminoprolines and (2S,4S)-4-arylamino-2-hydroxymethylpyrrolidines was studied \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2011, 60 (5), 873-881.pdf |
R 30 Reactions of 1,2,4,5-tetrazines with S-nuc / S. G. Tolshchina, R. I. Ishmetova, N. K. Ignatenko, A. V. Korotina, I. N. Ganebnuikh, V. A. Ol'shevskaya, V. N. Kalinin, G. L. Rusinov // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 985-991 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,2,4,5-TETRAZINES -- HETEROCYCLIC LEAVING GROUPS -- TETRAZINES Аннотация: The reactions of 3,6-disubstituted and azoloannulated 1,2,4,5-tetrazines containing heterocyclic leaving groups with S-nucleophiles were studied. The methods of introduction of functionalized thiols, including thiol derivatives of 1,7- and 1,2-dicarba-closo-dodecaboranes, into the tetrazine ring were developed. It was established for the first time that, instead of replacement of a leaving group in the tetrazine ring, the attack of S-nucleophile at the unsubstituted carbon atom occurs in the case of imidazo[1,2-b][1,2,4,5]tetrazines to form previously unknown products of nucleophilic substitution of the hydrogen atom \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2011, 60 (5), 985-991.pdf |
S 90 Study of oligomeric compounds of Urea-fotmaldehyde concentrate by ESI MS, IR and NMR spectroscopy / S. Y. Men'shikov, I. N. Ganebnuikh, M. S. Valova, L. S. Molochnikov // European Polymer Congress, Pisa, June 16-21 2013 : book of abstracts . - Pisa, Italy, 2013. - P2-107 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): SPECTROSCOPY -- OLIGOMERIZATION PRODUCTS -- NMR SPECTRA |
S 90 Study of oligomeric compounds of urea-formaldehyde concentrate by ESI MS, IR and NMR spectroscopy / S. Y. Men'shikov, I. N. Ganebnuikh, M. S. Valova, L. S. Molochnikov // European Polymer Congress, Pisa, June 16-21 2013 : book of abstracts . - Pisa, Italy, 2013. - С. 2-107 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): OLIGOMERIC COMPOUNDS -- UREA-FORMALDEHYDE -- NMR SPECTROSCOPY |