A 10 A route to fluorocontaining 1,3-thiazolines via internal polyfluorooxiranes [Electronic resource] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin, O. N. Chupakhin // Mendeleev Communications. - 1999. - N 6. - P231-232 . - ISSN 0959-9436 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reaction of internal fluoroolefin oxides with thiourea results in 2-amino-5-fluoro-4-hydroxy-4,5-di(polyfluoroalkyl)-1,3-thiazolines, providing a route to an unknown type of fluorine-containing thiazolines with two fluoroalkyl substituents |
S 98 Synthesis of Heterocycles Via Internal Polyfluorooxiranes [Text] : доклад, тезисы доклада / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin, O. N. Chupakhin // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P117 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
P 90 Preparation and reactions of 1,2- and 2,3-epoxy-2-chloro(bromo)6-hydrodecafluorohexanes [Text] / L. V. Saloutina, T. I. Filyakova, M. I. Kodess, A. Ya. Zapevalov // Journal of Fluorine Chemistry. - 1991. - Vol. 54, N 1-3. - P254 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
S 98 Synthesis of 2,3-bis(perfluoroalkyl)quinoxalines and 2,3-bis(perfluoroalkyl)-1,4-benzoxazines from oxides of internal perfluoroolefins [Electronic resource] / L. V. Saloutina, A. Ya. Zapevalov, V. I. Saloutin, M. I. Kodess, V. E. Kirichenko, M. G. Pervova, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2005. - Vol. 126, № 6. - P976-983 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reactions of oxides of internal trans-, cis-perfluoroolefins with o-phenylenediamine and 2-aminophenol in dioxane gave 2,3-bis(perfluoroalkyl)quinoxalines and 2,3-bis(perfluoroalkyl)-2H-1,4-benzoxazin-2-ols respectively in yields of 23–67%. When N,N-dimethylacetamide was used as a solvent an anionic isomerization of the oxides into ketones, which further yielded 2-(perfluoroalkyl)benzimidazoles in the case of o-phenylenediamine and 2-hydroxy-N-perfluoroalkanoylanilines in the case of 2-aminophenol, became the main path of these reactions. Unusual cyclization resulting in 2-pentafluoroethyl-2-pentafluoropropanoylbenzoxazolidine occurs on interaction between dodecafluoro-3,4-epoxyhexane and 2-aminophenol in N,N-dimethylacetamide. \\\\Expert2\\nbo\\Journal of Fluorine Chemistry\\2005, v.126, p.976.pdf |
A 10 A route to fluorocontaining N,S-heterocycles via octafluoro-2,3-epoxybutane [Text] / L. V. Saloutina, A. Ya. Zapevalov, V. I. Saloutin, P. A. Slepukhin, M. I. Kodess, V. E. Kirichenko, M. G. Pervova, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2007. - Vol. 128, № 7. - P769-778 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reaction of octafluoro-2,3-epoxybutane 1 with 2-aminothiophenol gave three kinds of novel fluorocontaining N,S-heterocyclic compounds depending on the solvent nature: 2,3-bis(trifluoromethyl)-3,4-dihydro-2H-1,4-benzothiazin-2-ol 2, 2-trifluoromethyl-2-[1-(2-aminophenylthio)-2,2,2-trifluoroethyl]-1,3-benzothiazolidine 6 and 5a,11a-bis(trifluoromethyl)-5a,6,11a,12-tetrahydro-5,11-dithia-6,12-diazanaphthacene 5. Use of the toluene, dioxane, tetrahydrofuran, acetonitrile and dimethoxyethane gave the unexpected dihydrobenzothiazine 2 (RS,SR RR,SS) in good to moderate yields. In dimethylsulfoxide and N,N-dimethylacetamide, unusual cyclization occurred resulting in benzothiazolidine 6 (RS,SR/RR,SS 1:1) in moderate yields. Formation of minor 1,1,1,3,4,4,4-heptafluoro-3-(2-aminophenylthio)-2,2-dihydroxybutane 4 which was converted into bis(benzothiazine) 5 was observed in all solvents tested with the exception of toluene and dioxane. The molecular structure of the RS,SR-diastereomer of dihydrobenzothiazine 2, bis(benzothiazine) 5 and the RS,SR-diastereomer of benzothiazolidine 6 has been established by X-ray crystallography. \\\\Expert2\\nbo\\Journal of Fluorine Chemistry\\2007, v.128. p.769.pdf |
P 80 Polyfluoroalkylated 1,3-thiazolines: synthesis from polyfluoro-2,3-epoxyalkanes [Text] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin, G. G. Aleksandrov, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2000. - Vol. 104, № 2. - P155-165 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The interaction of polyfluoro-2,3-epoxyalkanes with thiourea and thiosemicarbazide results in 2-amino-5-fluoro-4-hydroxy-4,5-di(polyfluoroalkyl)-1,3-thiazolines and 5-fluoro-2-hydrazino-4-hydroxy-4,5-di(polyfluoroalkyl)-1,3-thiazolines, respectively. Asymmetric oxiranes yield mixtures of regioisomers, and the ring opening has been found to occur mainly near the bulkier fluoroalkyl group. The reaction with thiourea proceeds stereospecifically in dimethyl sulfoxide. The molecular structure of E-isomers of 2-amino-5-fluoro-4-hydroxy-4,5-bis(trifluoromethyl)-1,3-thiazoline and 2-amino-5-fluoro-5-heptafluoropropyl-4-hydroxy-4-trifluoromethyl-1,3-thiazoline has been established by X-ray crystallography.???? |
F 94 From oxides of internal perfluoroolefins to fluorocontaining camphor thiazolinylhydrazones [Text] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, K. A. Lyssenko, M. Yu. Antipin, V. I. Saloutin, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2003. - Vol. 120, № 1. - P41-47 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reaction of oxides of internal trans- and cis-perfluoroolefins with (1S, 4S)- or racemic camphor thiosemicarbazone leads to the formation of trans- and cis-isomers of (1S, 4S)- or racemic camphor 5?-fluoro-4?-hydroxy-4?,5?-di(perfluoroalkyl)-1?,3?-thiazolinyl-2?-hydrazones, respectively. Unsymmetrical dodecafluoro-2,3-epoxyhexane yields a mixture of regioisomeric hydrazones. The molecular structure of the trans-isomer of (1S, 4S)-camphor 5?-fluoro-4?-hydroxy-4?,5?-bis(trifluoromethyl)-1?,3?-thiazolinyl-2?-hydrazone has been established by X-ray crystallography. The quite rare example of cocrystallization of two diastereomers of the latter in homochiral crystal (sp. group P21) has been revealed???? |
S 98 Synthesis of fluorine containing glycolurils and oxazolines from oxides of internal perfluoroolefins [Text] / L. V. Saloutina, A. Ya. Zapevalov, V. I. Saloutin, P. A. Slepukhin, M. I. Kodess, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2009. - Vol. 130, № 10. - P853-860 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): OXIDES OF INTERNAL PERFLUOROOLEFINS -- 1,5-bIS(PERFLUOROALKYL)TETRAAZABICYCLO[3.3.0]OCTANE-3,7-D Аннотация: The reaction of oxides of internal perfluoroolefins 1–3 with urea gave two kinds of novel fluorine containing N-heterocyclic compounds depending on the solvent nature: 1,5-bis(perfluoroalkyl)tetraazabicyclo[3.3.0]octane-3,7-diones 4a–c and 2-amino-5-fluoro-4,5-bis(perfluoroalkyl)-4,5-dihydrooxazol-4-ols 7a–d. Use of polar dimethylsulfoxide, N,N-dimethylacetamide and acetonitrile afforded glycolurils 4a–c in moderate yields. In dioxane, unexpected cyclization occurred resulting in oxazolines 7a–d in high yields. A similar reaction of oxiranes 2, 3 with urea in aqueous dioxane gave mixtures of 4,5-dihydroxy-4,5-bis(perfluoroalkyl)imidazolidine-2-ones 9b, c, glycolurils 4b, c and oxazolines 7b–d. The molecular structure of trans-isomers of oxazoline 7b and imidazolidine 9b has been established by X-ray crystallography?? \\\\Expert2\\nbo\\Journal of Fluorine Chemistry\\2009, V. 130, P. 853.pdf |
S 98 Synthesis of polyfluoroalkylated 1,4-diazinols and 1,4-oxazinols using polyfluoro-2,3-epoxyalkanes 32 + 13 [Text] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin // Journal of Fluorine Chemistry. - 1998. - Vol. 87, № 1. - P49-55. - Bibliogr. : p. 55 (13 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 2-AMINOETHANOL -- ETHYLENEDIAMINE -- POLYFLUORO-2,3-EPOXYALKANES -- POLYFLUOROALKYLATED 1,4-DIAZINOLS -- POLYFLUOROALKYLATED 1,4-OXAZINOLS Аннотация: It has been found that the reactions of polyfluoro-2,3-epoxyalkanes with ethylenediamine and 2-aminoethanol yield 2,3-di(polyfluoroalkyl)-1,5,6-trihydro-1,4-diazin-2-ols and 2,3-di(polyfluoroalkyl)-5,6-dihydro-1,4-oxazin-2-ols, respectively. In the case of unsymmetrical oxiranes mixtures of regioisomeric heterocyclic compounds have been obtained. These reactions were found to give some byproducts - N,N?-bis(polyfluoroacyl)ethylenediamines and N-polyfluoroacyl-2-aminoethanols. |
P 80 Polyfluoro-2,3-epoxyalkanes in reactions with thiourea and thiosemicarbazide [Text] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin, G. G. Aleksandrov, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2000. - Vol. 36, № 6. - P887-899. - Bibliogr. : p. 899 (17 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): POLYFLUORO-2,3-EPOXYALKANES -- THIOUREA -- THIOSEMICARBAZIDE Аннотация: Reactions of polyfluoro-2,3-epoxyalkanes with thiourea and thiosemicarbazide afforded 2-amino-4-hydroxy-4,5-di(polyfluoroalkyl)-5-fluoro-1,3-thiazolines and 2-hydrazino-4-hydroxy-4,5-di(polyfluoroalkyl)-5-fluoro-1,3-thiazolines respectively. Unsymmetrical oxiranes furnish mixtures of regioisomeric heterocyclic compounds, and the epoxy cycle is predominantly cleaved from the side of bulkier fluoroalkyl group. The reactions of E-oxiranes are stereospecific and provide 1,3-thiazolines in the E-form. The structure of compounds obtained was confirmed by IR, 19F, 1H, and 13C NMR spectroscopy, by mass spectra and chemical transformations. E-isomers of 2-amino-4-hydroxy-4,5-bis(trifluoromethyl)-5-fluoro-1,3-thiazoline and 2-amino-5-heptafluoropropyl-4-hydroxy-4-trifluoromethyl-5-fluoro-1,3-thiazoline were subjected to X-ray diffraction analysis. |
R 30 Reaction of 2,3-epoxyoctafluorobutane with 2-aminobenzenethiol [Electronic resource] / L. V. Saloutina, A. Ya. Zapevalov, V. I. Saloutin, M. I. Kodess, V. E. Kirichenko, M. G. Pervova, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2006. - Vol. 42, № 9. - P1307-1312. - Bibliogr. : p. 1312 (13 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 2,3-EPOXYOCTAFLUOROBUTANE -- 2-AMINOBENZENETHIOL -- EPOXY RING Аннотация: The reaction of 2,3-epoxyoctafluorobutane with 2-aminobenzenethiol in N,N-dimethylacetamide gave 3-(2-aminophenylsulfanyl)-1,1,1,3,4,4,4- heptafluorobutane-2,2-diol. In the reaction of the same compounds in dioxane, 2,3-bis(trifluoromethyl)-3,4-dihydro-2H-1,4-benzothiazin-2-ol was formed as a result of primary attack by the amino group in 2-aminobenzenethiol on the epoxy ring. The same product was obtained by treatment with 2-aminobenzenethiol of 2,3-bis(trifluoromethyl)-2H-1,4-benzoxazin-2-ol which was synthesized from 2,3-epoxyoctafluorobutane and 2-aminophenol. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2006, 42 (9), 1307.pdf |
R 30 Reaction of internal fluoroolefin oxides with camphor thiosemicarbazone [Electronic resource] / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2001. - Vol. 37, № 11. - P1522-1527. - Bibliogr. : p. 1527 (9 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): OXIDES -- FLUOROOLEFIN OXIDES -- CAMPHOR THIOSEMICARBAZONE -- DERIVATIVES -- EPOXY DERIVATIVES Аннотация: Epoxy derivatives of internal fluoroolefins (both cis and trans isomers) react in a stereospecific manner with (1S)-or rac-camphor thiosemicarbazone in a polar aprotic medium to give the corresponding 5-fluoro-4-hydroxy-4,5-bis(polyfluoroalkyl)thiazol-2-ylhydrazones. From unsymmetrical 2,3-epoxydodeca-fluorohexane a mixture of regioisomeric hydrazones is formed. According to the 1H and 19F NMR data, the resulting trans-hydrazones in (CD3)2SO and CDCl3 exist as mixtures of diastereoisomers occurring in a dynamic equilibrium. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2001, 37 (11), 1522.pdf |
R 30 Reactions of internal perfluoroolefin oxides with urea [Electronic resource] / L. V. Saloutina, A. Ya. Zapevalov, V. I. Saloutin, M. I. Kodess, P. A. Slepukhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2009. - Vol. 45, № 6. - P865-871. - Bibliogr. : p. 871 (19 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): OXIDES -- PERFLUOROOLEFIN OXIDES -- UREA -- HETEROCYCLES Аннотация: Internal perfluoroolefin oxides reacted with urea to give, depending on the solvent nature, two types of new fluorine-substituted nitrogen-containing heterocycles. 1,5-Bis(perfluoroalkyl)tetraazabicyclo[3.3.0]octane-3,7-diones were formed in dimethyl sulfoxide, N,N-dimethylacetamide, and acetonitrile, while the reaction in dioxane resulted in the formation of unexpected products, 2-amino-5-fluoro-4,5-bis(perfluoroalkyl)-4,5-dihydrooxazol-4-ols, existing mainly as trans isomers. trans Orientation of perfluoroalkyl substituents in these compounds was determined by analysis of 19F-19F spin-spin coupling constants in the 19F NMR spectra. The molecular structure of trans-2-amino-5-fluoro-4,5-bis(trifluoromethyl)-4,5-dihydrooxazol-4-ol was studied by X-ray analysis. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2009, 45 (6), 865.pdf |
R 30 Reactions of epoxides derived from internal perfluoroolefins with o-phenylenediamine and 2-aminophenol [Electronic resource] / L. V. Saloutina, A. Ya. Zapevalov, V. I. Saloutin, M. I. Kodess, V. E. Kirichenko, M. G. Pervova, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2006. - Vol. 42, № 4. - P558-566 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reactions of epoxy derivatives of internal perfluoroolefins with o-phenylenediamine and 2-aminophenol in dioxane gave 23–67% of the corresponding 2,3-bis(perfluoroalkyl)quinoxalines and 2,3-bis(perfluoroalkyl)-2H-1,4-benzoxazin-2-ols, respectively. When N,N-dimethylacetamide was used as a solvent, the main reaction pathway was anionic isomerization of epoxides into ketones which were then converted into 2-perfluoroalkylbenzimidazoles (in the reactions with o-phenylenediamine) or 2-hydroxy-N-perfluoroalkanoylanilines (in the reactions with 2-aminophenol). The reaction of 3,4-epoxydodecafluorohexane with 2-aminophenol in N,N-dimethylacetamide was accompanied by unusual cyclization to afford 2-pentafluoropropanoyl-2-pentafluoroethyl-1,3-benzoxazolidine \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2006, 42 (4), 558.pdf |
S 17 Saloutina, L. V. Reactions of 2,3-epoxypolyfluoroalkanes with triethylamine [Electronic resource] / L. V. Saloutina, M. I. Kodess, A. Ya. Zapevalov // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 1994. - Vol. 43, № 12. - P2057-2061 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reactions of 2,3-epoxyperfluoro- and 2,3-epoxy--hydropolyfluoroalkanes with excess triethylamine at elevated temperatures yield secondary alcohols, which are the reduction products of intermediate isomeric ketones. Ring-opening occurs preferentially from the side of the less bulky trifluoromethyl group in all compounds except 2,3-epoxy-6-hydroundecafluorohexane \\\\Expert2\\nbo\\Russian Chemical Bulletin\\1994, 43 (13), 2057-2061.pdf |
S 98 Synthesis of fluorine containing N-heterocycles using oxides of terminal perfluoroolefins and urea / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, P. A. Slepukhin, V. I. Saloutin, O. N. Chupakhin // Journal of Fluorine Chemistry. - 2012. - Vol.139. - С. 16-22 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): Me2SO -- PERFLUOROOLEFINS -- UREA Аннотация: The reaction of octafluoro-1,2-epoxybutane (1) with urea in Me2SO, aqueous Me2SO, aqueous dioxane, aqueous acetonitrile and of hexadecafluoro-1,2-epoxyoctane (2) with urea in aqueous Me2SO gave perfluoroalkylhydantoins – 5-hydroxy-5-pentafluoroethylimidazolidine-2,4-dione (4a) (yield 40–42%) and 5-hydroxy-5-tridecafluorohexylimidazolidine-2,4-dione (4b) (yield 54%), respectively. Use of dioxane and acetonitrile in the reaction of oxiranes 1, 2 with urea led to unexpected heterocyclic products – perfluoroalkyloxazoles 7a, b (yield 11–82%). Perfluoroalkyl containing allantoin – 5-tridecafluorohexyl-5-ureidoimidazolidine-2,4-dione (3b) (yield 19%) and polyfluoroalkyl containing urea–(2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoro-1-hydroxyheptyl)urea (6b) (yield 46%) have been first obtained by the reaction of oxirane 2 with urea in Me2SO and aqueous Me2SO, respectively \\\\Expert2\\nbo\\Journal of Fluorine Chemistry\\2012, v. 139, p.16.pdf |
S 98 Synthesis of fluorine-containing allantoins, hydantoins, and oxazolones from terminal perfluoroolefin oxides and urea / L. V. Saloutina, A. Ya. Zapevalov, M. I. Kodess, V. I. Saloutin, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2012. - Vol.48, №3. - С. 387-393 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ALLANTOINS -- HYDANTOINS -- OXAZOLONES Аннотация: 1,2-Epoxyoctafluorobutane reacted with urea in DMSO and aqueous DMSO, dioxane, and acetonitrile to give 40–42% of 5-hydroxy-5-pentafluoroethylimidazolidine-2,4-dione. 5-Hydroxy-5-tridecafluorohexylimidazolidine-2,4-dione was formed in 54% yield in analogous reaction of 1,2-epoxytridecafluorooctane with urea in aqueous DMSO. The reactions of 1,2-epoxyoctafluorobutane and 1,2-epoxytridecafluorooctane with urea in anhydrous dioxane and acetonitrile unexpectedly afforded heterocyclization products, 2-amino-5-fluoro-5-perfluoroalkyloxazol-4(5H)-ones (yield 11–82%). Fluorine-containing allantoin, 5-tridecafluorohexyl-5-ureidoimidazolidine-2,4-dione (yield 19%), and N-(1-hydroxy-2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptyl)-urea (yield 46%) were synthesized for the first time by reaction of 1,2-epoxytridecafluoroctane with urea in DMSO and aqueous DMSO \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2012, 48 (3), 387-393.pdf |
B 62 Bis(1,1,1,3,5,5,5-heptafluoro-4-iminopent-2-ene-2-aminato)copper(ii) — a new metal-containing matrix in the design of heterospin systems [Electronic resource] / S. V. Fokin, V. Ovcharenko, G. V. Romanenko, E. V. Tretyakov, A. S. Bogomyakov, V. I. Saloutin, T. I. Filyakova, L. V. Saloutina, V. N. Charushin, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2011. - Vol.60, №5. - С. 816-823. - Bibliogr. : p. 823 (11 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): COPPER(II) -- BISCHELATES -- NITROXIDES Аннотация: The first heterospin compounds based on bis(1,1,1,3,5,5,5 heptafluoro 4 iminopent 2 ene 2 aminato)copper(II) (CuL2) and nitronyl nitroxide radicals, 2 R 4,4,5,5 tetramethyl 4,5 dihydro 1H imidazole 3 oxide 1 oxyls (NIT R, where R = H, Me, Ph, and 1 methyl pyrazol 4 yl), were synthesized and structurally characterized. An important peculiarity of the structure of synthesized solid phases is the formation of a supramolecular structure due to hydrogen bonds between the oxygen atoms of the nitronyl nitroxide fragments of NIT R and the hydrogen atoms of the NH groups of CuL2 \\\\expert2\\NBO\\Russian Chemical Bulletin\\2011, 60 (5), 816-823.pdf |
Synthesis of fluorine-containing n,o-heterocycles on the base of 4,5-bis(trifluoromethyl)imidazolidine-2-ones, 2-aminoethanol and 2-aminophenol / L. V. Saloutina, M. I. Kodess, I. N. Ganebnykh [et al.] // Современные синтетические методологии для создания лекарственных препаратов и функциональных материалов" (MOSM 2021): V международная конференция: сборник тезисов. - Екатеринбург, 2021. - С. PR-96 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
Transformations of 4,5-bis(trifluoromethyl)imidazolidin-2-one and its N-substituted analogous in reactions with N,N-dinucleophiles / L. V. Saloutina, A. Y. Zapevalov, M. I. Kodess [et al.] // AIP conference proceedings. - 2022. - Vol. 2390. - Ст. 020069 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CHEMICAL COMPOUNDS Аннотация: 4,5-Dihydroxy-4,5-bis(trifluoromethyl)imidazolidin-2-one and its N-methyl(phenyl)-substituted analogous were synthesized by the reaction of perfluorobiacetyl with urea and methyl(phenyl)urea. Depending on a solvent nature and character of the substituent at N-atom of the imidazolidine, different trifluoromethyl-containing heterocycles were obtained in reactions of the imidazolidin-2-ones with thiosemicarbazide and guanidine carbonate: imidazothiazol, 1,2,4-triazines, and hydantoins. |