S 98 Synthesis of acyclic nucleosides based on 1,2,4-triazolo[3,2-c][1,2,4]triazin-7-ones [Electronic resource] / T. S. Shestakova, L. S. Lukyanova, T. A. Tseitler, S. L. Deev, E. N. Ulomskii, V. L. Rusinov, M. I. Kodess, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2008. - Vol. 57, № 11. - P2423-2430 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A new class of acyclic nucleosides based on 6-phenyl-1,2,4-triazolo[3,2-c][1,2,4]triazin-7-ones was synthesized and structurally characterized for the first time \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2008, 57 (11), 2423.pdf |
A 20 Addition of C-nucleophiles to 5-phenylpyrimidin-2(1H)-ones and 6-phenyl-1,2,4-triazin-3(2H)-one / I. N. Egorov, T. A. Tseitler, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // ARKIVOC. - 2011. - С. 323-334 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PHENYLPYRIMIDIN -- TRIAZINE -- NUCLEOPHILES \\\\Expert2\\nbo\\ARKIVOC\\2011, p.323.pdf |
R 30 Reaction of 3-phenyl-1,2,4-triazin-5(4H)-one under acylating conditions with natural alcohols containing an asymmetric carbon atom / I. N. Egorov, G. V. Zyryanov, P. A. Slepukhin, T. A. Tseitler, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2012. - Vol.48, №4. - С. 625-633 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CARBON ATOM -- NATURAL ALCOHOLS -- CHOLESTEROL Аннотация: This study describes the reactions of natural chiral alcohols such as borneol, isoborneol, cholesterol, and dihydrocholesterol with 3-phenyl-1,2,4-triazin-5(4H)-one in the presence of carboxylic acid anh \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2012, v.48, N 4, p.625-633.pdf |
C 52 Chichibabin-Type Condensation of Cyclic Ketones with 3-R-1,2,4-triazin-5(4H)-ones / I. N. Egorov, T. A. Tseitler, I. S. Kovalev, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Journal of Organic Chemistry. - 2012. - Vol.77, №14. - С. 6007-6013 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CYCLIC KETONES -- TRIAZINE -- KETONES Аннотация: Reactions between substituted 1,2,4-triazines and ketones were investigated. General procedures for one-pot synthesis of hydrogenated derivatives of such polycyclic systems as benzo[c][1,2,4]triazino[1,6-a][2]azecine, [1,2,4]triazino[1,6-f]phenantridine, and dicyclopenta[b,d]pyrido[1,2-f][1,2,4]triazine are described \\\\Expert2\\nbo\\Journal of Organic Chemistry\\2010, v.77, p.6007.pdf |
P 91 Preparation of triazatriphenylene cations, promising chemosensors for nitro compounds [Electronic resource] / D. S. Kopchuk, I. N. Egorov, T. A. Tseitler, A. F. Khasanov, I. S. Kovalev, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2013. - Vol.49, №3. - P503-505. - Библиогр.: с. 505 (10 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): TRIAZATRIPHENYLENE -- CATIONS -- NITRO COMPOUNDS \\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.49, N 3, p. 503-505.pdf |
A 89 Asymmetric Reactions of a Series of Aromatic Azines with Nucleophiles / I. N. Egorov, T. A. Tseitler, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // Heterocycles. - 2012. - Vol.86, №2. - С. 821-889 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): NUCLEOPHILIC ADDITION -- AZINE SERIES -- STEREOSELECTIVE FORMATION Аннотация: Current review is devoted to the reactions of nucleophilic addition in azine series, leading to the stereoselective formation of optically active products. Three types of reactions are reviewed: the reactions of achiral nucleophiles with chiral azines; the reactions of chiral nucleophiles with achiral azines; reactions of achiral nucleophiles with achiral azines in the presence of chiral catalysts |
S 98 Synthesis of New 1,3,4-Thiadiazines Capable of Inhibiting Nonenzymatic Glycosylation of Proteins [Electronic resource] / L. P. Sidorova, T. A. Tseitler, N. M. Perova, V. V. Emel’yanov, E. A. Savateeva, N. E. Maksimova, N. N. Mochul’skaya, V. A. Chereshnev, O. N. Chupakhin // Pharmaceutical Chemistry Journal. - 2015. - Vol. 49, № 8. - С. 501-505. - Bibliogr. : p. 505 (12 ref.) Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1,3,4-THIADIAZINE -- CYCLOCONDENSATION -- NONENZYMATIC GLYCOSYLATION OF PROTEINS -- THIOSEMICARBAZIDES Аннотация: A series of new 1,3,4-thiadiazines with cycloalkylamino (cyclopropylamino, cyclobutylamino, cyclopentylamino, cyclohexylamino) groups were synthesized via cyclocondensation of α-haloacetophenones with thiosemicarbazides containing 4-cycloalkyl groups. Five of the synthesized compounds showed the capability to inhibit nonenzymatic glycosylation of proteins in vitro in a model system. The obtained test results allowed compounds containing cyclopropylamino residues (LT-1a and LT-1d) to be recommended for further in vivo testing \\\\expert2\\nbo\\Pharmaceutical Chemistry Journal\\2015, 49 (8), 501-505.pdf |
1,3,4-thiadiazine derivates – antioxidants and protein glycation blockers – for correction of experimental diabetes mellitus / V. V. Emelyanov [и др.] // Experimental and computational biomedicine: Russian Conf. with Intern. Participation in memory of Prof. Vladimir S. Markhasin. - Екатеринбург : Изд-во Урал. ун-та, 2016. - С. 65 Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ Кл.слова (ненормированные): 1,3,4-THIADIAZINE -- ANTIOXIDANTS -- DIABETES MELLITUS |
T 89 Tseitler, T. A. 5-thienyl-2-cycloalkylamino-1,3,4-thiadiazines, hydrobromides / T. A. Tseitler, L. P. Sidorova, O. N. Chupakhin // Современные синтетические методологии для создания лекарственных препаратов и функциональных материалов (MOSM2018): вторая международная научно-практическая конференция : материалы и доклады. - Екатеринбург, 2019. - С. 109 Рубрики: ХИМИЧЕСКИЕ НАУКИ |