A 10 A Simple Method for Amination of 1,2,4-triazin-3(2H)-ones [Text] : доклад, тезисы доклада / O. N. Chupakhin, T. L. Pilicheva, G. V. Zyryanov, I. N. Egorov, V. L. Rusinov // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P148 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
О-42 1,2,4-triazinones in Interactions with C-nucleophiles [Text] : доклад, тезисы доклада / O. N. Chupakhin, G. V. Zyryanov, T. L. Pilicheva, V. L. Rusinov // International Memorial I.Postovsky Conference on Organic Chemisty, Ekaterinburg, March 17-20, 1998 : program and abstracts. - Ekaterinburg, 1998. - P149 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): 1.2.4-ТРИАЗИНОНЫ -- ВЗАИМОДЕЙСТВИЕ ХИМИЧЕСКОЕ -- ХИМИЧЕСКОЕ ВЗАИМОДЕЙСТВИЕ -- НУКЛЕОФИЛЫ -- C-НУКЛЕОФИЛЫ -- КОНФЕРЕНЦИИ -- ТЕЗИСЫ ДОКЛАДОВ -- ОРГАНИЧЕСКАЯ ХИМИЯ -- ХИМИЯ ОРГАНИЧЕСКАЯ |
D 62 Direct introduction of heterocyclic residues into 1,2,4-triazin-5(2H)-ones [Electronic resource] / V. L. Rusinov, G. V. Zyryanov, T. L. Pilicheva, O. N. Chupakhin, H. Neunhoeffer // Journal of Heterocyclic Chemistry. - 1997. - Vol. 34, N 3. - P1013-1019 Рубрики: ХИМИЧЕСКИЕ НАУКИ \\\\Cserver\\dist\\НБО\\Электронная библиотека_Библиогр1\\Journal of Heterocyclic Chemistry\\1997 v.34.p.1013. Chupakhin.pdf |
A 89 Asymmetric induction in the reactions of 3-aryl-1,2,4-triazin-5(4H)-ones with C-nucleophiles [Electronic resource] / I. N. Egorov, G. V. Zyryanov, E. N. Ulomskii, V. L. Rusinov, O. N. Chupakhin // Tetrahedron Letters. - 2006. - Vol. 47, № 42. - P7485-7487 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: 3-Aryl-1,2,4-triazin-5(4H)-ones, in the presence of N-protected amino acids, react with C-nucleophiles to form 1-acyl-6-Nu-3-aryl-1,6-dihydro-1,2,4-triazin-5(4H)-ones in high diastereomeric excess. This is the first case of the use of amino acids as chiral auxiliaries in nucleophilic additions to triazinones. \\\\Expert2\\nbo\\Tetrahedron Letters\\2006, v. 47, p.7485.pdf |
A 89 Asymmetric induction in the nucleophilic addition in the series of aromatic azines [Electronic resource] / I. N. Egorov, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // Russian Chemical Reviews. - 2005. - Vol. 74, № 12. - P1073-1087 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Stereoselective reactions of nucleophilic addition to the C=N bond in aromatic azines resulting in chiral products are reviewed. Various methods of inducing the optical activity are discussed. \\\\Expert2\\nbo\\Russian Chemical Reviews\\2005, V.74, p.1073.pdf |
D 62 Direct diastereoselective addition of l-menthol to activated 1,2,4-triazin-5(4H)-one [Text] / O. N. Chupakhin, G. V. Zyryanov, V. L. Rusinov, V. P. Krasnov, G. L. Levit, M. A. Koroleva, M. I. Kodess // Tetrahedron Letters. - 2001. - Vol. 42, № 12. - P2393-2395 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: For the first time in a triazine series it has been found that addition of a chiral O-nucleophile, l-menthol, to the C6-unsubstituted atom of 3-phenyl-1,2,4-triazin-5(4H)-one 1 activated by aliphatic acid anhydrides proceeds diastereoselectively to form a mixture of 1-acyl-6-[(1?R,3?R,4?S)-menthyl-3?)]-3-phenyl-(6S)-1,6-dihydro-1,2,4-triazin-5(4H)-ones 2 and 1-acyl-6-[(1?R,3?R,4?S)-menthyl-3?)]-3-phenyl-(6R)-1,6-dihydro-1,2,4-triazin-5(4H)-ones 3 in which the diastereomers 2 predominate. The diastereoselectivity of the process improves as the size of the N1-acyl substituent increases???? |
C 57 Chupakhin, O. N. Regioselectivity in the reactions of pyrroles with 3-aryl-1,2,4-triazin-5-ones [Electronic resource] / O. N. Chupakhin, G. V. Zyryanov, V. L. Rusinov // Mendeleev Communications. - 2001. - Vol. 11, № 2. - P77-78 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Depending on the nature of acylating agents, the reaction of 1-methylpyrrole with 3-aryl-1,2,4-triazin-5-ones leads to either ?- or ?-heteroarylpyrroles with a high degree of regioselectivity???? |
D 62 Direct diastereoselective introduction of l-menthol residue into 1,2,4-triazin-5(4H)-one [Electronic resource] / G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin, G. L. Levit, M. I. Kodess, T. S. Shtukina // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2004. - Vol. 53, № 6. - P1290-1294. - Bibliogr. : p. 1294 (16 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ACETIC ANHYDRIDE -- DIASTEREOSELECTIVITY -- ISOBUTYRIC ANHYDRIDE -- L-MENTHOL -- NUCLEOPHILIC ADDITION Аннотация: The reaction of 3-phenyl-1,2,4-triazin-5(4H)-one (1) with l-menthol in the presence of aliphatic acid anhydrides results in (6S)- and (6R)-1-acyl-6-(l- menth-3-yl)-1,6-dyhydro-3-phenyl-1,2,4-triazin-5(4H)-ones. The reaction is diastereoselective with predominant formation of (6S)-isomers. The reaction diastereoselectivity increases with enhancement of the steric hindrance in the vicinity of the reaction center of the azine. \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2004, 53 (6), 1290-1294.pdf |
S 98 Synthesis of 8-Aryl[1,2,4]triazolo[1,5-d][1,2,4]triazin-5(6H)-ones by S HN Reactions [Electronic resource] / V. L. Rusinov, G. V. Zyryanov, I. N. Egorov, E. N. Ulomskii, G. G. Aleksandrov, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2004. - Vol. 40, № 1. - P85-89 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: A new procedure has been proposed for the synthesis of 8-aryl[1,2,4]triazolo[1,5-d][1,2,4]-triazin-5(6H)-ones by reaction of 6-aryl-1,2,4-triazin-3(2H)-ones with hydrazides derived from aliphatic, aromatic, and heterocyclic carboxylic acids. The process invloves nucleophilic substitution of hydrogen (SN H)in aryltriazinones, oxidative closure of azole ring, and Dimroth rearrangement \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2004, 40 (1), 85.pdf |
Z 99 Zyryanov, G. V. Easy formation of S-N(H) products in reactions of indoles and pyrroles with 3-aryl-1,2,4-triazin-5(2H)-ones in the presence of tosyl chloride [Electronic resource] / G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya). - 2002. - Vol. 51, № 6. - P1042-1044 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The reactions of 3-aryl-1,2,4-triazin-5(2H)-ones with indoles and pyrroles in the presence of p-toluenesulfonyl chloride afforded 3-aryl-6-hetaryl-1,2,4-triazin-5(2H)-ones in high yields. The latter are products of the nucleophilic substitution of hydrogen \\\\Expert2\\nbo\\Russian Chemical Bulletin\\2002, 51 (6), 1042-1044.pdf |
A 18 Acid-base properties and prototropic tautomerism of isomeric 1,2,4-triazin-3- and -5-ones [Electronic resource] / I. V. Khabibulina, R. E. Trifonov, A.P. Volovodenko, M. S. Eremenkova, O. N. Chupakhin, V. L. Rusinov, G. V. Zyryanov, V. A. Ostrovskii // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2004. - Vol. 40, № 3. - P426-430. - Bibliogr. : p. 430 (40 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ACID -- BASE -- TRIAZINE DERIVATIVE -- AQUEOUS SOLUTION Аннотация: The acidity and basicity constants of isomeric phenyl(aryl)-1,2,4-triazin- 3- and -5-ones in aqueous solution were determined by spectrophotometry: pK a = 7.3-6.2; pKBH+ = 0.1 to -2.2. 1,2,4-Triazin-3-ones are weaker bases than the corresponding 1,2,4-triazin-5-ones. According to the AM1 calculations, the most thermodynamically favorable tautomer in the gas phase is the oxo form: namely, 2H-tautomers of the neutral bases and 2,4-H,H +-tautomers of the conjugate acids. \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2004, 40 (3), 426.pdf |
E 12 Easy synthesis of azacytosine derivatives [Text] / G. V. Zyryanov, T. L. Pilicheva, I. N. Egorov, V. L. Rusinov, O. N. Chupakhin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2000. - Vol. 36, № 4. - P602-604. - Bibliogr. : p. 604 (4 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): EASY SYNTHESIS -- DERIVATIVES -- AZACYTOSINE DERIVATIVES |
H 62 Heteroditopic receptors [Electronic resource] / N. A. Itsikson, G. V. Zyryanov, O. N. Chupakhin, A. I. Matern // Russian Chemical Reviews. - 2005. - Vol. 74, № 8. - P747-755 : рис., табл. Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Data on heteroditopic receptors, an important class of complexing agents, are surveyed. Attention is focused on the synthesis of the ligands and analysis of their binding properties. The influence of structural features on the properties of such systems is investigated |
A 20 Addition of C-nucleophiles to 5-phenylpyrimidin-2(1H)-ones and 6-phenyl-1,2,4-triazin-3(2H)-one / I. N. Egorov, T. A. Tseitler, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // ARKIVOC. - 2011. - С. 323-334 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PHENYLPYRIMIDIN -- TRIAZINE -- NUCLEOPHILES \\\\Expert2\\nbo\\ARKIVOC\\2011, p.323.pdf |
A 81 Aryne intermediates in the synthesis of polynuclear heterocyclic systems (Review) / I. S. Kovalev, D. S. Kopchuk, G. V. Zyryanov, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2012. - Vol.48, №4. - С. 536-547 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): ARYNE INTERMEDIATES -- DIENOPHILES -- DIELS-ALDER REACTIONS Аннотация: Published examples of the polynuclear fused heterocyclic systems production by cycloaddition reactions involving aryne intermediates generated in situ are reviewed \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2012, v.48, N 4, p.536-547.pdf |
R 30 Reaction of 3-phenyl-1,2,4-triazin-5(4H)-one under acylating conditions with natural alcohols containing an asymmetric carbon atom / I. N. Egorov, G. V. Zyryanov, P. A. Slepukhin, T. A. Tseitler, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2012. - Vol.48, №4. - С. 625-633 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CARBON ATOM -- NATURAL ALCOHOLS -- CHOLESTEROL Аннотация: This study describes the reactions of natural chiral alcohols such as borneol, isoborneol, cholesterol, and dihydrocholesterol with 3-phenyl-1,2,4-triazin-5(4H)-one in the presence of carboxylic acid anh \\\\Expert2\\nbo\\Chemistry of Heterocyclic Compounds\\2012, v.48, N 4, p.625-633.pdf |
P 91 Preparation of (benzo)isoquinolines using in situ generated aryne intermediates [Electronic resource] / D. S. Kopchuk, G. V. Zyryanov, I. S. Kovalev, V. L. Rusinov, I. N. Egorov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2013. - Vol.48, №12. - P1871-1873 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): (BENZO)ISOQUINOLINE -- 1,2,4-TRIAZINE -- ARYNE INTERMEDIATES -- CYCLOADDITION -- DIELS-ALDER REACTION \\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.48, N 12, p. 1871-1873.pdf |
P 91 Preparation of Pyridyl-substituted Monoazatriphenylenes [Electronic resource] / D. S. Kopchuk, G. V. Zyryanov, I. S. Kovalev, A. F. Khasanov, A. S. Medvedevskih, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2013. - Vol.49, №3. - P500-502. - Библиогр.: с. 502 (18 ref/) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): MONOAZATRIPHENYLENES -- PYRIDYL \\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.49, N 3, p. 500-502.pdf |
P 91 Preparation of triazatriphenylene cations, promising chemosensors for nitro compounds [Electronic resource] / D. S. Kopchuk, I. N. Egorov, T. A. Tseitler, A. F. Khasanov, I. S. Kovalev, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin // Chemistry of Heterocyclic Compounds. - 2013. - Vol.49, №3. - P503-505. - Библиогр.: с. 505 (10 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): TRIAZATRIPHENYLENE -- CATIONS -- NITRO COMPOUNDS \\\\expert2\\NBO\\Chemistry of Heterocyclic Compounds\\2013, v.49, N 3, p. 503-505.pdf |
A 10 A rational protocol for the synthesis of 1-(2-pyridyl)isoquinolines [Electronic resource] / D. S. Kopchuk, I. S. Kovalev, A. F. Khasanov, G. V. Zyryanov, P. A. Slepukhin, V. L. Rusinov, O. N. Chupakhin // Mendeleev Communications. - 2013. - Vol.23, №3. - С. 142-144. - Библиогр.: с. 144 (82 ref.) Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): SYNTHESIS -- ISOQUINOLINES -- X-RAY DIFFRACTION Аннотация: Aza-Diels-Alder reaction between 3-(2-pyridyl)-1,2,4-triazines and 1-morpholinocyclohexene followed by aromatization of the cyclohexene moiety affords 1-(2-pyridyl)isoquinolines. Crystal structures of two tetrahydroisoquinolines were confirmed by X-ray diffraction analysis |