F 70 Fluorine-containing heterocycles. XVII. (Tetrafluorobrnzoyl)thioureas in the synthesis of fluorine-containing azaheterocycles [Electronic resource] / G. N. Lipunova, E. V. Nosova, A. A. Laeva, T. V. Trashakhova, P. A. Slepukhin, V. N. Charushin // Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii). - 2008. - Vol. 44, № 5. - P741-749 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: Proceeding from (tetrafluorobenzoyl)thioureas fluorine-containing derivatives were synthesized of 1-aryl-2-ethylthioquinazolin-4-one, [1,3]benzothiazin-4-one, and also of thiazolidine and 1H-1,2,4-triazole \\\\Expert2\\nbo\\Russian Journal of Organic Chemistry\\2008, 44 (5), 741.pdf |
C 47 Charushin, V. N. Fluorinated derivatives of azaheterocycles [] / V. N. Charushin, E. V. Nosova, G. N. Lipunova // 20-th International Congress of Heterocyclic Chemistry, Palermo, July 31-August 5, 2005 : book of abstracts . - Palermo, Italy, 2005. - С. 506 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
B 78 Boron(III) Complexes with N,N'- and N,O-Heterocyclic Ligands: Synthesis and Spectroscopic Properties [Electronic resource] / G. N. Lipunova, E. V. Nosova, V. N. Charushin, O. N. Chupakhin // Comments on Inorganic Chemistry. - 2016. - Vol. 2016. - С. 1153470 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): PROPERTIES -- PREPARATION -- SYNTHETIC PREPARATION Аннотация: This review is focused on consideration of effects of the nature of N,N'- and N,O-bidentate ligands on the structure and optical properties of their B(III) complexes. It has been established that B(III) complexes with asym. N,N'- and N,O-bidentate ligands, such as ortho-hydroxyphenyl substituted azaheterocycles and heteryl-β-ketoimines, exhibit large Stokes shifts, enhanced intensity, and extended range for luminescence in solns. as well as in solid state, comparable with characteristics of the family of BODIPYs derivs. Complexes of some bidentate ligands can be considered as promising fluorophores for applications in biomedical imaging, electroluminescent, solar cell devices, and other fields. \\\\expert2\\nbo\\Comments on Inorganic Chemistry\\2016. P. 1153470.pdf |
C 57 Chupakhin, O. N. Scientific foundations for the creation of antiviral and antibacterial preparations [Electronic resource] / O. N. Chupakhin, V. N. Charushin, V. L. Rusinov // Herald of the Russian Academy of Sciences. - 2016. - Vol. 86, № 3. - С. 206-212 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): TRIAZIDE AND AZOLOAZINE DERIVATIVES -- TRIAZAVIRIN -- PROTEIN DISULFIDE ISOMERASE Аннотация: The results of the Ural scientific school's organic chemists on the creation of antiviral and antibacterial, including antitubercular, chemopreparations are considered. Basic research data were generalized on the synthesis and study of antiviral activity and the establishment of the metabolism and mechanism of azoloazine series compounds-azaanalogs of adenine and guanine, as well as their nucleosides, which led to the creation of a new family of antiviral substances. One of them, triazavirin, has become a regular therapeutic fixture as an antiflu preparation. The results of synthetic and biological studies on substituted pyrimidines, nucleosides of the benzimidazole and purine series, and other biologically active azaheterocycles are also discussed. \\\\expert2\\NBO\\Herald of the Russian Academy of Sciences\\2016. V. 86, N 3. P. 206-212.pdf |
V 29 Varaksin, M. V. Strategy of direct C(SP2)-H functionalization in non-aromatic azaheterocycles as an efficient approach towards novel 2H-imidazole derivatives / M. V. Varaksin, A. A. Akulov, T. D. Moseev, O. N. Chupakhin, V. N. Charushin // Современные синтетические методологии для создания лекарственных препаратов и функциональных материалов (MOSM2018): вторая международная научно-практическая конференция : материалы и доклады. - Екатеринбург, 2019. - С. 139-140 Рубрики: ХИМИЧЕСКИЕ НАУКИ |
Azaheterocyclic derivatives of ortho - carborane: synthetic strategies and application opportunities / L. A. Smyshliaeva, M. V. Varaksin, V. N. Charushin, O. N. Chupakhin // Synthesis. - 2020. - Vol. 52, № 3. - P337-352 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): AZAHETEROCYCLES -- CARBORANES -- CARBORYNE -- CROSS-COUPLING REACTIONS -- DECABORANE Аннотация: Azaheterocyclic derivatives of 1,2-dicarba- closo -dodeca borane (ortho -carborane) are known to be of particular interest due to numerous plausible applications, particularly, in medicine, materials science, and advanced technologies. Three principal synthetic strategies resulting in azaheterocyclic carboranes, in which boron-enriched and azaheterocyclic fragments are linked to each other, either directly by means of the C-C bonds or through a short spacer (CH 2, CH 2 S, CH 2 O, etc.), have been outlined. These synthetic approaches are of general character and can be used both individually and in combination to afford promising organoboron clusters of diverse architectures. 1 Introduction 2 C-C Cross-Coupling Strategies in the Synthesis of Azahetero cyclic Carboranes 3 Carboryne-Based Transformation Strategies 4 Condensation Strategies: Reactions of Decaborane B 10 H 14 with Substituted Acetylenes 5 Conclusion and Outlook. |
Azaheterocyclic derivatives of ortho -carborane: synthetic strategies and application opportunities / L. A. Smyshliaeva, M. V. Varaksin, V. N. Charushin, O. N. Chupakhin // Synthesis. - 2020. - Т. 52, № 3. - P337-352 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): CARBORANES -- AZAHETEROCYCLES -- DECABORANE -- CROSS-COUPLING REACTIONS -- CARBORYNE Аннотация: Azaheterocyclic derivatives of 1,2-dicarba- closo -dodeca borane (ortho -carborane) are known to be of particular interest due to numerous plausible applications, particularly, in medicine, materials science, and advanced technologies. Three principal synthetic strategies resulting in azaheterocyclic carboranes, in which boron-enriched and azaheterocyclic fragments are linked to each other, either directly by means of the C-C bonds or through a short spacer (CH 2, CH 2 S, CH 2 O, etc.), have been outlined. These synthetic approaches are of general character and can be used both individually and in combination to afford promising organoboron clusters of diverse architectures. 1 Introduction 2 C-C Cross-Coupling Strategies in the Synthesis of Azahetero cyclic Carboranes 3 Carboryne-Based Transformation Strategies 4 Condensation Strategies: Reactions of Decaborane B 10 H 14 with Substituted Acetylenes 5 Conclusion and Outlook. |
Direct c-li/c-h coupling of c6f5li with azines and azoles n-oxides as efficient approach toward to polyfloorinated azaheterocycles / T. D. Moseev, M. V. Varaksin, E. A. Virlova [et al.] // Actual problems of organic chemistry and biotechnology. - Екатеринбург, 2020. - P276-277 Рубрики: ХИМИЧЕСКИЕ НАУКИ Кл.слова (ненормированные): C-C COUPLING -- NUCLEOPHILIC SUBSTITUTION OF HYDROGEN -- FLUORINE -- FLUORARENES |
C-H functionalization in non-aromatic azaheterocycles. an effective approach in the design of promising molecules for medicinal chemistry / M. V. Varaksin, L. A. Smyshliaeva, T. D. Moseev [и др.] // MedChem-Russia 2021: материалы 5-ой Российской конференции по медицинской химии с международным участием. - Волгоград, 2021. - С. 16 Рубрики: ХИМИЧЕСКИЕ НАУКИ |