Инвентарный номер: нет. T 44 Role of alpha-fetoprotein in differentiation of regulatory t-lymphocytes / V. A. Chereshnev, V. P. Timganova, S. A. Zamorina [et al.] // Doklady Biological Sciences. - 2017. - Vol. 477. - P248-251 Рубрики: ХИМИЧЕСКИЕ НАУКИ Аннотация: The effect of native а-fetoprotein (AFP) on the expression of T-regulatory lymphocyte (Treg) markers by activated CD4+ lymphocytes with different proliferative status was studied. а-Fetoprotein did not affect the ratio of proliferating and non-proliferating activated CD4+ cells. In the study of Treg differentiation, it was found that AFP at concentrations of 50 and 100 mg/mL significantly inhibited the number of non-proliferating CD4+FOXP3+ and CD4+FOXP3+HELIOS+ lymphocytes without affecting the expression of Treg markers by proliferating CD4+ lymphocytes. \\\\Expert2\\NBO\\Doklady Biological Sciences\\2017. - Vol. 477 - P. 248-251.pdf |