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Общее количество найденных документов : 211
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1.
Инвентарный номер: нет.
   
   E 27


   
    Effects of myelopeptides on immune response and morphometrical manifestations of inflammation in experimental penetrating wound of the eye / N. L. Berkasova, T. V. Gavrilova, Yu. I. Shilov [et al.] // Bulletin of experimental biology and medicine. - 2008. - Vol. 145, № 3. - P341-343
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
MYELOPEPTIDES -- MYELOPID -- PENETRATING WOUND OF THE EYE
Аннотация: Myelopid and MP-1 myelopeptide increase the count of antibody-producing cells, reduced under the effect of injury and standard therapy, and do not modify the suppression of delayed hypersensitivity. Injections of myelopid and MP-3 together with standard drugs optimized the traumatic inflammation processes

\\\\expert2\\nbo\\Bulletin of Experimental Biology and Medicine\\2008, v.145, N 3, p. 341.pdf
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2.
Инвентарный номер: нет.
   
   K 75


    Korolevskaya, L. V.
    Alkylhydroxybenzenes modify immune complex size [Electronic resource] / L. V. Korolevskaya, K. V. Shmagel, V. A. Chereshnev // Doklady biochemistry and biophysics. - 2012. - Vol. 446, № 1. - P229-230. - Bibliogr. : p. 230 (9 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
ALKYLHYDROXYBENZENES -- IMMUNE COMPLEX

\\\\expert2\\NBO\\Doklady Biochemistry and Biophysics\\2012, v.446, № 1. p.229-230.pdf
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3.
Инвентарный номер: нет.
   
   P 93


   
    Proliferativeresponse of lymphocyte to pokeweed mitogen depends on the concentration of endogenous cortisol in the early post-traumatic period in patients with penetrating eye injury / V. A. Chereshnev, Yu. I. Shilov , T. V. Gavrilova [et al.] // Bulletin of experimental biology and medicine. - 2012. - Vol. 153, № 5. - P722-725. - Bibliogr. : p. 724-725 (15 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
LYMPHOCYTES -- CORTISOL -- PENETRATING EYE INJURY
Аннотация: The intensity of lymphocyte proliferation in response to pokeweed mitogen depends on cortisol level in the peripheral blood in the early post-traumatic period of penetrating eye injury. Lymphocyte proliferation in 72- and 96-h cultures from patients with high levels of endo genous hormone was suppressed. In 120-h cultures, the intensity of proliferation remains unchanged. Lymphocyte blast transformation was increased in 120-h cultures from patients with normal cortisol concentration and remained unchanged in case of low cortisol level

\\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2012, v.153, N 5, p. 722-725.pdf
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4.
Инвентарный номер: нет.
   
   E 97


   
    Expression of TLR9 and BD-2 protein genes in corneal cells of mice of different strains with herpetic keratitis / V. A. Chereshnev, L. V. Gankovskaya, L. V. Koval'chuk [et al.] // Bulletin of experimental biology and medicine. - 2012. - Vol. 153, № 2. - P236-239. - Bibliogr. : p. 239 (11 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
INNATE IMMUNITY -- HERPETIC INFECTION -- KERATITIS
Аннотация: The dynamics of gene expression of two proteins, TLR9 (one of the key receptors recognizing CpG repeats of herpes virus DNA) and beta-defensin 2 (antibacterial peptide), was studied on the model of herpetic keratitis in C57Bl/6 and BALB/c mice. New data on differences in TLR9 gene expression in mice of the two strains infected with the virus were obtained. Reduced TLR9 gene expression in the cornea of C57Bl/6 mice was associated with their high sensitivity to infection caused by herpes simplex 1 virus

\\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2012, v.153, N 2, p. 236-239.pdf
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5.
Инвентарный номер: нет.
   
   M 99


   
    Myelopeptides regulate the microbicidic and secretory activities of Innate immunity effectors / V. A. Chereshnev, S. V. Gein, L. S. Mazunina [et al.] // Doklady biochemistry and biophysics. - 2011. - Vol. 436, № 1. - P53-55. - Bibliogr. : p. 55 (9 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
MYELOPEPTIDES -- MICROBICIDIC -- INNATE iMMUNITY

\\\\expert2\\NBO\\Doklady Biological Sciences\\2011. V. 436, N 1.P. 53-55.pdf
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6.
Инвентарный номер: нет.
   
   R 30


   
    Reaction diffusion modelling of interferon distribution in secondary lymphoid organs / G. Bocharov, A. Danilov, Y. Vassilevski [et al.] // Mathematical modelling of natural phenomena. - 2011. - Vol. 6, № 7. - P13-26
ББК Ч2
Рубрики: НАУКА. НАУКОВЕДЕНИЕ
Кл.слова (ненормированные):
SYSTEMS -- RECIRCULATION -- LYMPHOCYTES
Аннотация: This paper proposes a quantitative model of the reaction-diffusion type to examine the distribution of interferon-alpha (IFN alpha) in a lymph node (LN). The numerical treatment of the model is based on using an original unstructured mesh generation software Ani3D and nonlinear finite volume method for diffusion equations. The study results in suggestion that due to the variations in hydraulic conductivity of various zones of the secondary lymphoid organs the spatial stationary distribution of IFN alpha is essentially heterogeneous across the organs. Highly protected domains such as sinuses, conduits, co-exist with the regions in which where the stationary concentration of IFN alpha is lower by about 100-fold. This is the first study where the spatial distribution of soluble immune factors in secondary lymphoid organs is modelled for a realistic three-dimensional geometry

\\\\expert2\\nbo\\Mathematical Modelling and Natural Phenomena\\2011. Vol.6, №7. С. 13-26.pdf
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7.
Инвентарный номер: нет.
   


   
    Modulation of Cytokine secretion and oxidative metabolism of innate immune effectors by Rhodococcus Biosurfactant / V. A. Chereshnev, S. V. Gein, T. A. Baeva [et al.] // Bulletin of experimental biology and medicine. - 2010. - Vol. 149, № 6. - P734-738
Кл.слова (ненормированные):
RHODOCOCCUS RUBBEr -- GLYCOLIPID BIOSURFACTANT -- INTERLEUKIN-10
Аннотация: The glycolipid biosurfactant complex from Rhodococcus ruber IEGM 231 had a stimulatory effect on the production of IL-12, IL-18, and reactive oxygen species by cells of the innate immunity. This effect depended on the composition of cell cultures and presence of LPS. It was primarily observed in non-stimulated cultures. The glycolipid biosurfactant complex had little effect on IL-10 secretion by monocytes and mononuclear cells

\\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2010, v.149, N 6, p. 734-738.pdf
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8.
Инвентарный номер: нет.
   
   R 87


    Rozental', O. M.
    A normative model of balanced nature management [Electronic resource] / O. M. Rozental', V. A. Chereshnev // Russian Journal of Ecology. - 2010. - Vol. 41, № 4. - P356-363. - Bibliogr. : p. 363 (13 ref.)
ББК Ч2
Рубрики: НАУКА. НАУКОВЕДЕНИЕ
Кл.слова (ненормированные):
MEASURING CONTROL -- TRACEABILITY -- VARIABILITY OF CONTROLLED PARAMETERS
Аннотация: The risk of erroneous regulation in multilevel normative environmental chains, at the federal, regional, and lower levels, down to the corporate one, has been studied. This risk has been demonstrated to increase unacceptably rapidly in the framework of the existing system of "unconditional acceptance" of normative standards. To mend the situation, it is necessary to use the "conditional acceptance" model by regarding post hoc decisions made at higher levels as a priori ones at the next (lower) levels. A strategy of environmentally and economically balanced corporate regulation of nature management through minimization of the losses resulting from both excessive caution and breaching the existing regulations has been proposed. This system, combined with the European approach to nature conservation, requires that the "riskless" regulation should be abandoned and is expected to improve the parameters of nature management quality by three to four orders of magnitude

\\\\expert2\\NBO\\Russian Journal of Ecology\\2010. V. 41, N 4. P. 356-363.pdf
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9.
Инвентарный номер: нет.
   
   S 54


    Shmagel, K. V.
    Molecular bases of immune complex pathology [Electronic resource] / K. V. Shmagel, V. A. Chereshnev // Biochemistry. - 2009. - Vol. 74, № 5. - P469-479. - Bibliogr. : p. 477-479 (126 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
IMMUNE COMPLEXES -- COMPLEMENT -- CR1 RECEPTORS
Аннотация: The binding of antigens with antibodies forms immune complexes in the body. Usually these complexes are eliminated by the system of mononuclear phagocytes without development of pathological changes. This review highlights principal mechanisms responsible for safe removal of immune complexes in primates and humans. Special attention is given to diseases known as "immune complex diseases", when antigen-antibody complexes induce inflammatory reactions. The review considers key experimental works that significantly contributed to current knowledge of etiology and pathogenesis of type III hypersensitivity. Some factors of the development of immune complex syndrome such as level of humoral immune response to antigen, isotype and affinity of forming antibodies, the amount of immune complexes, and the consequences of their interaction with the complement system and Fc-receptors are analyzed based on the molecular mechanisms involved. The review contains a retrospective analysis of the most significant scientific achievements in immune complex pathology investigation within the last 100 years

\\\\expert2\\NBO\\Biochemistry\\2009, v.74, p. 469-479.pdf
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10.
Инвентарный номер: нет.
   
   I-60


   
    Inflammation markers in atherosclerosis development / A. P. Shavrin, Y. V. Khovaeva, V. A. Chereshnev, B. V. Golovskoy // Cardiovascular therapy and prevention. - 2009. - Vol. 8, № 3. - P13-15
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
CONGESTIVE-HEART-FAILURE -- TUMOR-NECROSIS-FACTOR -- DEPENDENT VASODILATION
Аннотация: To study different inflammation markers at various stages of atherosclerosis progression. Material and methods. In 174 21-70-year-old people, brachial artery ultrasound (Aloka 5000) was performed to Visualize atherosclerotic plaques and assess intima-media thickness (IMT). Immuno-enzyme analysis was used to measure plasma levels of C-reactive protein, CRP (SeroELISA test system, Diagnostic Systems Laboratories, USA), and cytokines - tumor necrosis factor alpha (THF-alpha), interleukins 1, 4 and 8 (1L-1, 2, and 8) (Russian test systems, Cytokine company, St. Petersburg

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