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Общее количество найденных документов : 21
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 1-10    11-21   21-21 
1.
Инвентарный номер: нет.
   
   E 97


   
    Expression of TLR9 and BD-2 protein genes in corneal cells of mice of different strains with herpetic keratitis / V. A. Chereshnev, L. V. Gankovskaya, L. V. Koval'chuk [et al.] // Bulletin of experimental biology and medicine. - 2012. - Vol. 153, № 2. - P236-239. - Bibliogr. : p. 239 (11 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
INNATE IMMUNITY -- HERPETIC INFECTION -- KERATITIS
Аннотация: The dynamics of gene expression of two proteins, TLR9 (one of the key receptors recognizing CpG repeats of herpes virus DNA) and beta-defensin 2 (antibacterial peptide), was studied on the model of herpetic keratitis in C57Bl/6 and BALB/c mice. New data on differences in TLR9 gene expression in mice of the two strains infected with the virus were obtained. Reduced TLR9 gene expression in the cornea of C57Bl/6 mice was associated with their high sensitivity to infection caused by herpes simplex 1 virus

\\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2012, v.153, N 2, p. 236-239.pdf
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2.
Инвентарный номер: нет.
   
   M 99


   
    Myelopeptides regulate the microbicidic and secretory activities of Innate immunity effectors / V. A. Chereshnev, S. V. Gein, L. S. Mazunina [et al.] // Doklady biochemistry and biophysics. - 2011. - Vol. 436, № 1. - P53-55. - Bibliogr. : p. 55 (9 ref.)
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
MYELOPEPTIDES -- MICROBICIDIC -- INNATE iMMUNITY

\\\\expert2\\NBO\\Doklady Biological Sciences\\2011. V. 436, N 1.P. 53-55.pdf
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3.
Инвентарный номер: нет.
   


   
    Modulation of Cytokine secretion and oxidative metabolism of innate immune effectors by Rhodococcus Biosurfactant / V. A. Chereshnev, S. V. Gein, T. A. Baeva [et al.] // Bulletin of experimental biology and medicine. - 2010. - Vol. 149, № 6. - P734-738
Кл.слова (ненормированные):
RHODOCOCCUS RUBBEr -- GLYCOLIPID BIOSURFACTANT -- INTERLEUKIN-10
Аннотация: The glycolipid biosurfactant complex from Rhodococcus ruber IEGM 231 had a stimulatory effect on the production of IL-12, IL-18, and reactive oxygen species by cells of the innate immunity. This effect depended on the composition of cell cultures and presence of LPS. It was primarily observed in non-stimulated cultures. The glycolipid biosurfactant complex had little effect on IL-10 secretion by monocytes and mononuclear cells

\\\\expert2\\NBO\\Bulletin of Experimental Biology and Medicine\\2010, v.149, N 6, p. 734-738.pdf
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4.
Инвентарный номер: нет.
   
   C 51


    Chereshnev, V. A.
    Beta-endorphin as the endogenous regulator of immune processes / V. A. Chereshnev, S. V. Gein // Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova. - 2009. - Vol. 95, № 12. - P1279-1290
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
BETA ENDORPHIN -- OPIATE RECEPTOR -- ADAPTIVE IMMUNITY
Аннотация: Endogenous opioid peptides represent the group of bioregulatory factors possessing a wide range of biologically active effects. One of most essential functions of endogenous opioids appears to be the realization of cellular interaction between nervous and immune systems. Beta-endorphin is a peptide hormone that is the most active and multi-functional representative of the opioid peptide family. This review summarizes current observations on the nature ofbeta-endorphin, its production by the immune system cells, opiate receptor structure and expression, as well as the peptide effect on the processes of cellular activation, proliferation, and differentiation in innate and adaptive immunity

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5.
Инвентарный номер: нет.
   
   I-56


   
    Impact of bacterial autoregulatory molecules (homoserine lactones and alkylhydroxybenzenes) on the oxidative metabolism of the cell effectors of natural immunity / D. G. Deryabin, T. G. Sviridova, G. I. El'-Registan, V. A. Chereshnev // Microbiology. - 2013. - Vol. 82, № 2. - P133-141
ББК 57
Рубрики: БИОЛОГИЧЕСКИЕ НАУКИ
Кл.слова (ненормированные):
ALKYLHYDROXYBENZENES -- CHEMOLUMINESCENCE -- HOMOSERINE LACTONES
Аннотация: We investigated the impact of bacterial regulators homoserine lactones (HSLs) and alkylhydroxybenzenes (AHBs) (which are present in human fluids at pico- and nanomolar concentrations) on neutrophile oxidative metabolism. The HSL and AHB effects were determined using a test based on induced luminol-dependent chemoluminescence of neutrophiles in human peripheral blood. In this test, neutrophiles were preincubated with chemical analogs of bacterial autoregulators with different lengths of the hydrocarbon radical, such as HSL · HCl, C6- and C12-HSL, and C1-, C6-, and C12-AHB. We revealed that they suppressed the chemoluminescence and, accordingly, the oxidative metabolism of neutrophiles. This effect was more significant with HSLs than with AHBs. Within each of the two groups, the effect increased with an increase in the length of the hydrocarbon chain of the homologues. High concentrations of long-chain autoregulators of both types produce a cytotoxic effect that is associated with apoptosis in the case of C12-HSL and with cell membrane damage in the case of C12-AHB. The effects of low HSL and AHB concentrations involve their protein-modifying properties and result in changes in the activities of neutrophile oxidative enzymes. To a lesser extent, these effects are due to the pro- and antioxidant activities of HSLs and AHBs, respectively. In light of the results obtained, the HSL and AHB effects are to be considered as a novel mechanism of regulating the activities of cell effectors of natural innate immunity. In symbiotic and parasitic systems, the mechanism involves the bimodal pattern of the effects of HSLs and AHBs that vary depending on their structure and concentrations

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6.
Инвентарный номер: нет.
   
   I-55


   
    Immunomodulation of injury and stress-induced immunological disorders in penetrating wound of the eye / M. V. Chereshneva, Yu. I. Shilov , T. V. Gavrilova, S. V. Gein, V. A. Chereshnev // Vestnik oftalmologii. - 2006. - Vol. 122, № 2. - P42-46
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
IMMUNOSUPPRESSIVE AGENT -- ANIMAL -- CELLULAR IMMUNITY

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7.
Инвентарный номер: нет.
   
   N 52


   
    New capacities of the phagocytic test used in pediatric phthisiology / L. P. Sanakoeva, A. D. Koriukina, V. A. Chereshnev, V. A. Aksenova // Probl Tuberk Bolezn Legk . - 2004. - №6. - P42-48
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
BCG VACCINE -- LUNG TUBERCULOSIS -- PHAGOCYTOSIS
Аннотация: The paper presents the results of a study of the phagocytic activity of leukocytes (PAL) in 98 healthy children, vaccinated with BCG, in different periods after immunization and in 68 children with tuberculous infection (39 children with tuberculosis and 29 Mycobacterium tuberculosis-infected children). An improved procedure for studying PAL was used, in which sheep erythrocytes of two types ("antigenic" and those with a complex of antigen + antibody + antigen), which may differentiate the phase of bacteremia and immune synthesis, were used as an object for phagocytes. In the limited number of vaccinated children, bacteremia were detectable up to 9 months; the phase of immune synthesis continued in most children up to 3 years. The study has demonstrated that a complex of phagocytic tests may be used for the early diagnosis of tuberculous infection, for the evaluation of a tuberculous process and antituberculous immunity

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8.
Инвентарный номер: нет.
   
   S 54


    Shmagel, K. V.
    Modern view on immunology of periodontitis / K. V. Shmagel, O. V. Beliaeva , V. A. Chereshnev // Stomatologiia. - 2003. - Vol. 82, № 1. - P61-64
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
ANTIBODY PRODUCTION -- CELLULAR IMMUNITY -- PERIODONTITIS

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9.
Инвентарный номер: нет.
   
   M 45


   
    Mechanisms of changes in the hemoglobin profile during acute adaptation to extreme conditions / V. A. Chereshnev, M. N. Sumin, A. V. Rezaikin, B. G. Yushkov // Bulletin of experimental biology and medicine. - 2002. - Vol. 134, № 3. - P223-225
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
ADAPTIVE IMMUNITY -- ERYTHROCYTE HETEROGENEITY -- HEMOGLOBIN ISOFORMS
Аннотация: We studied changes in rat hemoglobin isoforms during acute adaptation to various hypoxic conditions. Erythrocytes were heterogeneous in the content of various hemoglobin isoforms. Changes in the hemoglobin profile during hypoxia are related to variations in the ratio between populations of erythrocytes differing in the content of individual hemoglobin isoforms

\\\\expert2\\nbo\\Bulletin of Experimental Biology and Medicine\\2002, V.134, N 3, p. 223-225.pdf
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10.
Инвентарный номер: нет.
   
   T 44


   
    The influence of bacterial autoregulation molecules (homoserine lactones and alkyloxybenzoles) on oxidative metabolism of the natural immunity cellular effectors. [Electronic resource] / D. G. Deryabin, T. G. Sviridova, G. I. El'-Registan, V. A. Chereshnev // Mikrobiologiia. - 2013. - Vol. 82, № 2. - P147-156
ББК 61
Рубрики: ЗДРАВООХРАНЕНИЕ. МЕДИЦИНСКИЕ НАУКИ
Кл.слова (ненормированные):
ANTIOXIDANT -- BENZENE -- DRUG DERIVATIVE

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